Results 121 to 130 of about 5,049,311 (291)

Revista mensual del Centro Región Leonesa: Revista mensual del Centro Región Leonesa - Año V Número 49 - 1924 marzo (01/03/1924)

open access: yes, 1924
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Revista mensual del Centro Región Leonesa: Revista mensual del Centro Región Leonesa - Año III Número 30 - 1922 junio (01/06/1922)

open access: yes, 1922
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Revista mensual del Centro Región Leonesa: Revista mensual del Centro Región Leonesa - Año V Número 51 - 1924 julio (01/07/1924)

open access: yes, 1924
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core  

Caracterización fisicoquímica y distribución agroecológica del durazno (Prunus persica) en la región grandes montañas

open access: yesRevista Biológico Agropecuaria Tuxpan
Este estudio tuvo como objetivo evaluar el estado actual del cultivo de duraznos (Prunus persica) en la región de las grandes montañas. El área de estudio comprendió el municipio de Alpatláhuac, Veracruz, y las comunidades de Xicola y Ayahualulco.
María del Rosario Dávila Lezama   +4 more
doaj   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Front Matter Vol. 19 No.1 (2024)

open access: yesRegion: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif
Jurnal Region
doaj   +1 more source

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