Results 111 to 120 of about 5,049,311 (291)
En este estudio se determinó el nivel mÃnimo de compensación por el cual los productores de la región Izta-Popo aceptarÃan renunciar a actividades extractivas del bosque para conservar el bosque y mantener los servicios hidrológicos ambientales. La Disposición a Aceptar (DAA) se obtuvo con el método de Valoración Contingente, comparando la DAA
Diego Armando Martínez-Cruz +5 more
openaire +2 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core
El objetivo del presente trabajo fue caracterizar los componentes tecnológicos y socioeconómicos en los agroecosistemas con bovinos de doble propósito de la Región del Papaloapan, Veracruz, México. Se diseño y aplicó entrevistas semi-estructuradas a productores en las Asociaciones Ganaderas Locales y en ranchos ganaderos de los 21 municipios de ...
Julio Vilaboa-Arroniz +5 more
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source

