Results 111 to 120 of about 6,134,931 (285)
La valoración de los parámetros del suelo es fundamental para identificar la productividad de las unidades de producción agrícola. Estos parámetros no solo influyen en el crecimiento y desarrollo de los cultivos, sino que también determinan la ...
Marali Anaid García Castillo +4 more
doaj +1 more source
El presente trabajo tiene como objetivo el de ofrecer un análisis de la ocupación paleolítica de las sociedades cazadoras-recolectores en la Región Geohistórica del Estrecho de Gibraltar, especialmente en los espacios que denominamos ‘’ambientes montañosos’’, marcados estos por su caracterización geográfica y geológica.
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Back Matter Vol. 18 No.2 (2023)
Jurnal Region
doaj
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Sea surface temperature and the distribution and apparent abundance of skipjack (Katsuwonus pelamis) in the Eastern Pacific Ocean, 1951-1968 [PDF]
ENGLISH: Isograms of sea surface temperature (OC) have been produced for 1949-1968 for the areas of the eastern Pacific Ocean in which the majority of the skipjack catch is taken. These are in the immediate coastal zone, California (35° N) to Chile (20 0
Williams, F.
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Región Sur Argentina: el Movimiento Social después del reflujo Daniel Campione Argentina Brasil Chile Paraguay ...
CLACSO, Consejo Latinoamericano de Ciencias Sociales - Compilador/a o Editor/a
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

