Results 91 to 100 of about 5,362,876 (283)
Revista mensual del Centro Región Leonesa: Revista mensual del Centro Región Leonesa - Año III Número 30 - 1922 junio (01/06/1922) [PDF]
, 1922 Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
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JEADV Clinical PracticePatients with severe Recessive Dystrophic Epidermolysis Bullosa (RDEB) present facial contractures that hinder the delivery of standard treatment strategies such as occlusal splints for bruxism.
Susanne Krämer +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Revista Biológico Agropecuaria TuxpanLos ciatostominos son los principales nematodos gastrointestinales (NGI) que afectan a los caballos, su control se basa en el uso de antihelmínticos (AH); sin embargo, a nivel mundial se ha reportado resistencia a los AH. Por tanto, es necesario conocer
Maricarmen Gómez-Lorenzo +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Revista Atlántica-Mediterránea de Prehistoria y ArqueologÃa Social, 2015 El presente trabajo tiene como objetivo el de ofrecer un análisis de la ocupación paleolítica de las sociedades cazadoras-recolectores en la Región Geohistórica del Estrecho de Gibraltar, especialmente en los espacios que denominamos ‘’ambientes montañosos’’, marcados estos por su caracterización geográfica y geológica.
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Back Matter Vol. 18 No.2 (2023)
Region: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023 Jurnal Region
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source