Results 81 to 90 of about 5,049,311 (291)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Revista mensual del Centro Región Leonesa: Revista mensual del Centro Región Leonesa - Año III Número 22 - 1921 julio (01/07/1921)

, 1921
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Evaluación de la susceptibilidad de nematodos gastrointestinales a la ivermectina en equinos del Norte de Veracruz

Revista Biológico Agropecuaria Tuxpan
Los ciatostominos son los principales nematodos gastrointestinales (NGI) que afectan a los caballos, su control se basa en el uso de antihelmínticos (AH); sin embargo, a nivel mundial se ha reportado resistencia a los AH. Por tanto, es necesario conocer
Maricarmen Gómez-Lorenzo , Melina Maribel Ojeda Chi , Marco Antonio Alarcón Zapata , Dora Romero Salas , Abigail Tabarez Rojas   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Adjunctive Botulinum Toxin Type A for Bruxism and Sweat‐Worsened Facial Blistering in Recessive Dystrophic Epidermolysis Bullosa: A Case Series

JEADV Clinical Practice
Patients with severe Recessive Dystrophic Epidermolysis Bullosa (RDEB) present facial contractures that hinder the delivery of standard treatment strategies such as occlusal splints for bruxism.
Susanne Krämer, Sebastián Véliz, Gina Pennacchiotti, Fernanda Salazar, María‐Beatriz Méndez   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

[Artículo traducido] La edad influye en la eficacia de la transferencia autóloga osteocondral: resultados prometedores para pacientes menores de 40 años

Revista Española de Cirugía Ortopédica y Traumatología
Resumen: Antecedentes: Investigaciones previas en las que se ha utilizado el trasplante osteocondral autólogo (OAT) han mostrado peores resultados con el aumento de la edad del paciente. El objetivo de este artículo es evaluar a una cohorte de pacientes
F. Figueroa, D. Figueroa, R. Calvo, E. Stocker, M. Itriago, M. Nuñez   +5 more
doaj   +1 more source

Distribución del Canon Minero y su incidencia en los Indicadores de Desarrollo Humano Región Ancash 2004-2014: Una propuesta de redistribución

INGnosis Revista de Investigación Científica, 2015
En el presente estudio se hace una revisión de las principales características y los montos de la distribución del canon minero y como estos, tanto en su forma más generalizada de aplicación como en las unidades de análisis, tiene correlación positiva o negativa, con el objetivo de determinar si han logrado o no mejorar los indicadores de ...
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source