Results 101 to 110 of about 4,842,470 (311)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Optimal Management with Potential Regime Shifts [PDF]
We analyze how the threat of a potential future regime shift affects optimal management. We use a simple general growth model to analyze four cases that involve combinations of stock collapse versus changes in system dynamics, and exogenous versus ...
De Zeeuw, A. +2 more
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Liquid pinching dynamics in an inertial transitioning regime
Physical Review ResearchThe pinching of a liquid filament at low viscosity, whether in air or liquid, shows a rich and interesting behavior. The liquid thread thins according to a capillary-inertial regime power law at the beginning, before transitioning into other regimes when
A. Said Ismail, Nilofar Taraki
doaj +1 more source
UNEMPLOYMENT DYNAMICS IN SPAIN, A REGIONAL ANALYSIS WITH A MARKOV REGIME SWITCHING APPROACH
Journal of Smart Economic Growth, 2022 The aim of this paper is to analyze the Spanish unemployment dynamics, on national and regional levels, with a Markov Regime Switching model on quarterly data from 2002 to 2020.
Wissem Boukraine
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Nature CommunicationsOne of the central challenges in condensed matter physics is to comprehend systems that have strong disorder and strong interactions. In the strongly localized regime, their subtle competition leads to glassy electron dynamics which ceases to exist well ...
Shashank Kumar Ojha +12 more
doaj +1 more source
This book develops a diagnostic framework for a cluster of phenomena that are usually treated as unrelated: the stasis at the frontier of theoretical physics, the persistent pluralism of the social sciences, the retreat of grand philosophical narratives, the fragmentation of public discourse, and the proliferation of pseudo-theoretical symbolic ...
openaire +2 more sources
On real interest rate dynamics and regime switching
, 2008 We find evidence of regime switching dynamics in the USA and the UK real interest rates over the period 1881-2003. For the UK, there is a regime in which the real interest rate displays a relatively stronger mean-reversion and a regime in which it ...
Kanas, Angelos, Angelos Kanas
core +1 more source
Multiphase computational fluid dynamics–conjugate heat transfer for spray cooling in the non-boiling regime [PDF]
, 2017 A numerical study is described to predict, in the non-boiling regime, the heat transfer from a circular flat surface cooled by a full-cone spray of water at atmospheric pressure.
S Jafari +21 more
core +1 more source