Results 121 to 130 of about 4,842,470 (311)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The Homological Kähler-de Rham Differential Mechanism: II. Sheaf-Theoretic Localization of Quantum Dynamics

Advances in Mathematical Physics, 2011
The homological Kähler-de Rham differential mechanism models the dynamical behavior of physical fields by purely algebraic means and independently of any background manifold substratum.
Anastasios Mallios, Elias Zafiris
doaj   +1 more source

Exchange Rates and Markov Switching Dynamics [PDF]

This article presents a systematic and extensive empirical study on the presence of Markov switching dynamics in three dollar-based exchange rates. A Monte Carlo approach is adopted to circumvent the statistical inference problem inherent to the test of ...
Yin-Wong Cheung, Ulf G. Erlandsson
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Modelling Regime Switching and Structural Breaks with an Infinite Dimension Markov Switching Model [PDF]

This paper proposes an infinite dimension Markov switching model to accommodate regime switching and structural break dynamics or a combination of both in a Bayesian framework.
Yong Song
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

SPATIAL AND TEMPORAL DISTRIBUTION OF TWO ANACRONEURIA SPECIES (PLECOPTERA: PERLIDAE) IN A NEOTROPICAL RIVER OF COLOMBIA

Acta Biológica Colombiana
Ecological studies on habitat use patterns on the distribution of Plecoptera species facilitate the understanding of this population dynamics. Our objective was to determine the distribution and abundance of Anacroneuria caraca Stark, 1995 and A.
Yesely Hurtado-Borrero, Cesar E. Tamaris-Turizo, Maria del Carmen Zúñiga   +2 more
doaj   +1 more source

Real convergence and regime-switching among EU accession countries [PDF]

, 2008
Real convergence among the ten EU 2004 accession economies is investigated with respect to long-run real interest parity. We employ a novel approach where unit-root tests for real interest differentials are embedded within a Markov regime-switching ...
Holmes, Mark J., Holmes, M, Wang, Ping; id_orcid, Wang, Ping   +3 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Inferring Supply Chain Plasticity from a Social–Ecological Systems Perspective: A Regime-Conditioned Probabilistic Framework

Systems
Supply chain plasticity (SCP) is a critical dynamic capacity through which firms respond to disruptions by reconfiguring their supply chains. Its latent, regime-dependent nature makes SCP difficult to identify.
Zhigang Lu, Xinyao Feng, Hua Jiang
doaj   +1 more source