Results 71 to 80 of about 4,842,470 (311)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Scientific basis for the Arctic ice regime shipping system
, 1996 This paper proposes a system dynamics approach to the development of a scientific basis for the Arctic Ice Regime Shipping System. This approach considers the structure of the entire system, and formulates the parts of the system as compatible ...
Williams, F. M.
core +1 more source
Regime-switching models for electricity spot prices: Introducing heteroskedastic base regime dynamics and shifted spike distributions [PDF]
, 2009 We calibrate Markov regime-switching (MRS) models to mean daily spot prices from the EEX market. Our empirical study shows that (i) models with shifted spike regime distributions lead to more realistic models of electricity spot prices and that (ii ...
Weron, Rafal, Janczura, Joanna
core +2 more sources
Two-Phase Bubble Columns: A Comprehensive Review
ChemEngineering, 2018 We present a comprehensive literature review on the two-phase bubble column; in this review we deeply analyze the flow regimes, the flow regime transitions, the local and global fluid dynamics parameters, and the mass transfer phenomena.
Giorgio Besagni +2 more
doaj +1 more source
A two regime model of inflation and unemployment fluctuations [PDF]
In this paper we present a formal definition of the notions of economic regime and regime dynamics. Starting from these definitions, we discuss a multiple regime dynamic model generating an endogenous unemployment-price adjustment mechanism.
Juan Gabriel Brida
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Exchange Rate Dynamics Under Stochastic Regime Shifts: A Unified Approach [PDF]
Techniques of regulated Brownian motion are used to analyze the behavior of the exchange rate when official policy reaction functions are subject to future stochastic changes.
Kenneth A. Froot, Maurice Obstfeld
core
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source