Results 91 to 100 of about 1,121,804 (297)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Superradiant Laser: First-Order Phase Transition and Non-stationary Regime
, 1998 We solve the superradiant laser model in two limiting cases. First the stationary low-pumping regime is considered where a first-order phase transition in the semiclassical solution occurs. This discontinuity is smeared out in the quantum regime. Second,
Haake, Fritz +2 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Retroactivity induced operating regime transition in an enzymatic futile cycle. [PDF]
PLoS One, 2021 Parundekar A, Viswanathan GA.
europepmc +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Regime Shift Associated with the 2004-2008 US Housing Market Bubble.
PLoS ONE, 2016 The Subprime Bubble preceding the Subprime Crisis of 2008 was fueled by risky lending practices, manifesting in the form of a large abrupt increase in the proportion of subprime mortgages issued in the US.
James Tan, Siew Ann Cheong
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
New Journal of Physics, 2017 We study kinetic effects responsible for the transition to relativistic self-induced transparency in the interaction of a circularly-polarized laser-pulse with an overdense plasma and their relation to hole-boring (HB) and ion acceleration.
E Siminos +3 more
doaj +1 more source
Formulas for Friction Factor in Transitional Regimes [PDF]
Journal of Hydraulic Engineering, 2008 This note concerns variations of the friction factor in the two transitional regimes, one between laminar and turbulent flows and the other between fully smooth and fully rough turbulent flows. An interpolation approach is developed to derive a single explicit formula for computing the friction factor in all flow regimes.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source