Results 141 to 150 of about 5,304,157 (297)

Brainstem dysfunction induced by laser-induced shock wave results in hippocampal CA3 neuronal injury in mice. [PDF]

Front Neurol
Nagamura T, Seno S, Kiriu N, Motegi M, Kawauchi S, Tomura S, Kiyozumi T.   +6 more
europepmc   +1 more source

Regional Metamorphism

, 2005
Feenstra, A., Franz, G.
openaire   +3 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Effects of the thermic treatment of the retam honey in the El- Oued region on some physical and chemical properties [PDF]

, 2019
Djilani Ghemam Amara, Alia Zaid, Kharraz Khaled, Khezzane Khadidja, Lakhan Latifa, Mesbahi Mohammed Adel, Rebiai Abdelkrim   +6 more
openalex   +1 more source

Clinical Significance of Conjunctival Microvascular Density in Diabetic Retinopathy: A Multimodal Correlation Study Based on Swept-Source Optical Coherence Tomography Angiography. [PDF]

J Diabetes Res
Huang X, Yu J, Zou W, Xiang X, Liu H.
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Mechanisms of Managing Regional Ethnic and Political Processes (on the Example of Saratov Region)

, 2014
Andrey Soldatkin
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Preliminary Motions: Mountain View Regional Water Services Commission et al. v. Director, Central Region, Regional Services, Alberta Environment re: Capstone Energy Ltd.

, 2006
Alberta Environmental Appeals Board Decisions
openalex   +2 more sources

Financial inclusion and extreme poverty in the MENA region: a gap analysis approach [PDF]

, 2020
Noha Emara, Mahmoud Mohieldin
openalex   +1 more source