Results 171 to 180 of about 17,585,100 (417)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

EVALUATION WITHOUT BIAS: A METHODOLOGICAL PERSPECTIVE ON PERFORMANCE MEASURES FOR BUSINESS INCUBATORS [PDF]

open access: yes
Business growth and formation are fundamental drivers of job crea-tion and economic growth. Business incubators provide a nurturing environment, through an array of business support resources and services, where entrepre-neurs, start-ups, and small ...
Peter V. SCHAEFFER, Shaoming CHENG
core  

Spotlight on Essex County 2010 Winter [PDF]

open access: yes, 2010
Articles about Essex County, Ontario, on topics such as the Nisei farm camps, Camp Cedarwin, Faithville, and the underground railroad.https://scholar.uwindsor.ca/swoda-windsor-region/1103/thumbnail ...
Essex Free Press
core   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Back Matter Vol. 18 No.2 (2023)

open access: yesRegion: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023
Jurnal Region
doaj  

TESTING THE NEG MODEL : FURTHER EVIDENCE FROM PANEL DATA [PDF]

open access: yes
Local wage variations in the UK are explained by two non-nested rival hypotheses. The first derives from new economic geography theory, in which wages depend on market access.
Bernard FINGLETON
core  

Fifty Years Forward With Ford [PDF]

open access: yes, 1953
50 year retrospective of the Ford Motor Company from 1903-1953.https://scholar.uwindsor.ca/swoda-windsor-region/1010/thumbnail ...
Ford Motor Company
core   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

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