Results 171 to 180 of about 8,796,441 (309)

Diverse ossification pathways in the lower jaw of Sclerocephalus (Lower Permian) as revealed by the first record of chondroid bone in Amphibia. [PDF]

Sci Rep
Konietzko-Meier D, Klein N.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Schwerpunkt: Investitionen

, 2015
Koch, Andreas, Krumm, Raimund
core  

Ulnar-evoked motor activity recorded over the abductor pollicis brevis region in carpal tunnel syndrome: a preliminary case series. [PDF]

Front Hum Neurosci
Vághy B, Várbíró S.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Hot Deformation Behavior and Microstructure Evolution of a Novel Near-α Titanium Alloy with Initial Lamellar Microstructure During Hot Compression. [PDF]

Materials (Basel)
Jiang X, Wu L, Sun T, Zhou J.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Revised draft environmental impact statement: Lower Mississippi region comprehensive study

Lower Mississippi RegionComprehensive Study Revised DraftEnvironmental Impact Statement1975This appendix is one of a series of 22 documents conyrising the complete Lower Mississippi Region Conprehensive Study.
Lower Mississippi Region Comprehensive Study Coordinating Committee
core  

Global Antimicrobial Non-Susceptibility Patterns of <i>Streptococcus pneumoniae</i>: A Systematic Literature Review (2014-2023) Stratified by Age, Region, and Infection Type. [PDF]

Infect Drug Resist
Bhuiyan MU, Carter JA, Abbing-Karahagopian V.   +2 more
europepmc   +1 more source