Results 191 to 200 of about 17,585,100 (417)

INTERREGIONAL R&D SPILLOVERS IN EUROPE [PDF]

open access: yes
Our paper identifies and estimates the effects of R&D spillovers on total factor productivity with consideration of spatial effects. We first run our estimations on the Coe and Helpman (1995) model introducing spatial correlation.
Diègo LEGROS, Myriam ABDELMOULA
core  

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

URBAN STRUCTURE: ITS ROLE IN URBAN GROWTH, NET NEW BUSINESS FORMATION AND INDUSTRIAL CHURN [PDF]

open access: yes
Cities are the “engines of growth” because entrepreneurial and cre-ative activities are concentrated in cities. This suggests that cities grow by host-ing new businesses and “churning” industries advantageously.
Bumsoo LEE, Peter GORDON
core  

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

ON THE RELATIONSHIPS BETWEEN SPATIAL CLUSTERING, INEQUALITY, AND ECONOMIC GROWTH IN THE UNITED STATES : 1969-2000 [PDF]

open access: yes
The literature on economic development has been divided as to the nature of the relationship between inequality and growth. Recent exploratory work in the field has provided evidence that the dynamic and spatial relationships between the two may be far ...
Mark V. JANIKAS, Sergio J. REY
core  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

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