Results 21 to 30 of about 5,304,157 (297)

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan   +5 more
wiley   +1 more source

Happiness in Romanian cities on the road from post-communism transition to EU accession

open access: yesREGION, 2016
The literature on life satisfaction in transition countries, and in particular on Romania, demonstrated that life satisfaction significantly differs across rural communities and cities of different size.
Camilla Lenzi, Giovanni Perucca
doaj   +1 more source

Regional Growth and Regional Decline [PDF]

open access: yes, 2014
Since the early 1990s, there has been a renaissance in the study of regional growth, spurred by new models, methods, and data. We survey a range of modeling traditions, and some formal approaches to the hard problem of regional economics; namely, the joint consideration of agglomeration and growth. We also review empirical methods and findings based on
Breinlich, Holger   +2 more
openaire   +6 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

The CHilean Internal Migration (CHIM) database: Temporally consistent spatial data for the analysis of human mobility

open access: yesREGION, 2017
Changes in zonal boundaries and coding schemes severely compromise temporal comparison of data. In Chile, the Population and Housing census is the only comprehensive source of internal migration data, but municipal boundaries and occupation and industry ...
Francisco Rowe
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

Cities and Inequality

open access: yesREGION, 2016
We propose an innovative methodology to measure inequality between cities. If an even distribution of amenities across cities is assumed to increase the average well-being in a given country, inequality between cities can be evaluated through a ...
Alessandra Michelangeli, Eugenio Peluso
doaj   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu   +20 more
wiley   +1 more source

Macroeconomic determinants of Port and Douro wine exports: An econometric approach

open access: yesREGION, 2020
This study analyses recent trends (2006-2018) in Port and Douro wine exports and estimates their macroeconomic determinants. The results of the gravity equation reveal that the purchasing power in importing countries is the most important export ...
Anthony Macedo   +2 more
doaj   +1 more source

Regional differences [PDF]

open access: yeseLife, 2017
The skin is a complex landscape containing regions in which hair follicles exhibit different types of behavior.
Zhou Yu, Ting Chen
openaire   +3 more sources

Home - About - Disclaimer - Privacy