Results 61 to 70 of about 5,304,157 (297)

An Overview of Urbanization in Ecuador under Functional Urban Area Definition

open access: yesREGION, 2018
This paper explores the urbanization process under Functional Urban Areas (FUAs) definition considering Ecuador as case of study. Analyzing data from 1950 to 2010, we have identified 28 FUAs that confirm that urbanization has rapidly increased in Ecuador
Moises Obaco Alvarez   +1 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Editorial Special Issue: Urban Freight, land use planning and public administration strategies

open access: yesREGION, 2018
Well-being and economic growth are strictly correlated. Cities are the engines of an innovation-based economy where research and new ideas are the core input of production. Urbanisation is becoming synonymous of economic growth. People flock into cities,
Valerio Gatta   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Editorial: REGION - the online open-access journal of ERSA

open access: yesREGION, 2014
This editorial launches REGION, the new online and open-access journal of ERSA. REGION aims to be a high-quality academic journal in the field of regional science.
Julia Koschinsky   +4 more
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Panel Data Models of New Firm Formation in New England

open access: yesREGION, 2017
This study examines the impact of the determinants of new firm formation in New England at the county level from 1999 to 2009. Based on the Spatial Durbin panel model that accounts for spillover effects, it is found that population density and human ...
Jitendra Parajuli, Kingsley E. Haynes
doaj   +1 more source

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