Results 81 to 90 of about 8,796,441 (309)

REGIONAL THEORY AND REGIONAL MODELS

open access: yesPapers in Regional Science, 1962
The ideas outlined in this paper are tentative and only partially developed. They have arisen very much as a response to the deficiencies in existing regional models. Whether this particular structure can lead to added order and power in such models remains to be demonstrated.
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

La incidencia del miedo en las formas de inclusión y exclusión de la población en condición de desplazamiento en Medellín

open access: yes, 2004
IP 7272-10-12450Incluye anexosM., Luz Amparo Sanchez M. -- Medellin : Corporacion Region, 204. -- 244p. ; 21 cm. -- ISBN 9588134242. --;ARTICULO(S) EN REVISTA: La percepcion social de los desplazados: un asunto de la politica publica / Marta;Ines Villa. -
Sánchez Medina, Luz Amparo   +1 more
core   +1 more source

Editorial Special Issue: Urban Freight, land use planning and public administration strategies

open access: yesREGION, 2018
Well-being and economic growth are strictly correlated. Cities are the engines of an innovation-based economy where research and new ideas are the core input of production. Urbanisation is becoming synonymous of economic growth. People flock into cities,
Valerio Gatta   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Editorial: REGION - the online open-access journal of ERSA

open access: yesREGION, 2014
This editorial launches REGION, the new online and open-access journal of ERSA. REGION aims to be a high-quality academic journal in the field of regional science.
Julia Koschinsky   +4 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

LAWS EASTERN REGION OF NIGERIA 1959 VOLUME I [PDF]

open access: yes, 1959
A brief description on the the ordinances of Eastern region of Nigeria and subsidiary legislation made thereunder assented to in Her Majesty’s name this 17th day of February, 1959.PART1 -INSTRUMENT AMENDING THE INSTRUMENT ESTABLISHING THE OGUTA RURAL ...
Eastern Region of Nigeria
core  

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