Results 81 to 90 of about 9,092,180 (307)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Back Matter Vol. 18 No.1 (2023)

open access: yesRegion: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023
Jurnal Region
doaj   +1 more source

An Overview of Urbanization in Ecuador under Functional Urban Area Definition

open access: yesREGION, 2018
This paper explores the urbanization process under Functional Urban Areas (FUAs) definition considering Ecuador as case of study. Analyzing data from 1950 to 2010, we have identified 28 FUAs that confirm that urbanization has rapidly increased in Ecuador
Moises Obaco Alvarez   +1 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Verkehr in der Region Hannover [PDF]

open access: yes, 2005
VERKEHR IN DER REGION HANNOVER Verkehr in der Region Hannover / Amme, Florian [Bearb.] (Rights reserved) (-
Amme, Florian [Bearb.]
core  

Editorial Special Issue: Urban Freight, land use planning and public administration strategies

open access: yesREGION, 2018
Well-being and economic growth are strictly correlated. Cities are the engines of an innovation-based economy where research and new ideas are the core input of production. Urbanisation is becoming synonymous of economic growth. People flock into cities,
Valerio Gatta   +2 more
doaj   +1 more source

The Pacific Rim: Region or regions?

open access: yesPapers of the Regional Science Association, 1990
Given the dynamic nature of the Pacific Rim, the Pacific Regional Science Conference Organization (PRSCO) has a unique opportunity to both grow with the region and contribute solutions to the problems which come with growth. This paper first examines some of the economic attributes of the Pacific Region and then explores some of the challenges and ...
openaire   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Editorial: REGION - the online open-access journal of ERSA

open access: yesREGION, 2014
This editorial launches REGION, the new online and open-access journal of ERSA. REGION aims to be a high-quality academic journal in the field of regional science.
Julia Koschinsky   +4 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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