Results 91 to 100 of about 14,433,678 (306)

Uncovering Norway’s regional disparities with respect to natural riches

open access: yesREGION, 2015
This study aims at unveiling regional development differences in Norway with respect to various natural resource-based activities that take place in the NUTS 3 regions.
Sevil Acar, Burhan Can Karahasan
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

EMPIRICS OF THE METROPOLITAN PRODUCTIVITY PATTERNS IN EUROPE [PDF]

open access: yes
This paper focuses on the main European metropolitan areas and builds empirics on their evolution over the process of economic integration these last twenty years.
Christian LONGHI
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

TESTING THE NEG MODEL : FURTHER EVIDENCE FROM PANEL DATA [PDF]

open access: yes
Local wage variations in the UK are explained by two non-nested rival hypotheses. The first derives from new economic geography theory, in which wages depend on market access.
Bernard FINGLETON
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

EVALUATION WITHOUT BIAS: A METHODOLOGICAL PERSPECTIVE ON PERFORMANCE MEASURES FOR BUSINESS INCUBATORS [PDF]

open access: yes
Business growth and formation are fundamental drivers of job crea-tion and economic growth. Business incubators provide a nurturing environment, through an array of business support resources and services, where entrepre-neurs, start-ups, and small ...
Peter V. SCHAEFFER, Shaoming CHENG
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Regions, regionalisms and identities:towards a regional mess

open access: yes, 2017
Abstract This chapter seeks to interrogate the transformation of regions, in order to tease out the sometimes paradoxical relationship between various approaches to conceptualising space. It aims to connect discussions on different kinds of regions and regionalisms, considering both deinstitutionalisation and institutionalisation processes. The chapter
openaire   +1 more source

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