Results 91 to 100 of about 8,796,441 (309)

Capital stock in Spain and its distribution by territories (1964-2012)

open access: yesREGION, 2015
Since 1995 the BBVA Foundation and the Ivie have been conducting an extensive research program on Spanish economic growth. The regularly-updated database "Capital stock in Spain and its distribution by territories" are the basis of this program ...
Matilde Mas   +2 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Dar es salaam Declaration on Peace,Security and Democracy and Development in the Great lakes region,First summit of Heads of state and Governrments draft 2

open access: yes, 2008
Document collected by the University of Texas Libraries from the web-site of the Reseau Documentaire International Sur La Region Des Grands Lacs Africains (International Documentation Network on the Great African Lakes Region).
INTERNATIONAL CONFERENCE FOR THE GREAT LAKES REGION
core  

Was bringt die Region der Region? [PDF]

open access: yes, 2012
WAS BRINGT DIE REGION DER REGION? Was bringt die Region der Region? (Rights reserved) (-

core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Juan Manuel Barragán Muñoz [PDF]

open access: yesRevista de Estudios Andaluces, 1986
Aportación al estudio de la región portuaria andaluza
doaj   +1 more source

Regions, regionalisms and identities:towards a regional mess

open access: yes, 2017
Abstract This chapter seeks to interrogate the transformation of regions, in order to tease out the sometimes paradoxical relationship between various approaches to conceptualising space. It aims to connect discussions on different kinds of regions and regionalisms, considering both deinstitutionalisation and institutionalisation processes. The chapter
openaire   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Vague regions

open access: yes, 1997
In many geographical applications there is a need to model spatial phenomena not simply by sharp objects but rather through indeterminate or vague concepts. To support such applications we present a model of vague regions which covers and extends previous approaches. The formal framework is based on a general exact model of spatial data types.
Erwig, Martin, Schneider, Markus
openaire   +2 more sources

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