Results 101 to 110 of about 14,433,678 (306)
ON POTENTIALIZED PARTIAL FINITE DIFFERENCE EQUATIONS: ANALYZING THE COMPLEXITY OF KNOWLEDGE-BASED SPATIAL ECONOMIC DEVELOPMENTS [PDF]
Knowledge-based regional and urban studies are plentiful; some systematics might be in order at this junction, so first the different links between economic production units in geographical space have to be clearly defined.
Alain SALLEZ +3 more
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
INTERREGIONAL R&D SPILLOVERS IN EUROPE [PDF]
Our paper identifies and estimates the effects of R&D spillovers on total factor productivity with consideration of spatial effects. We first run our estimations on the Coe and Helpman (1995) model introducing spatial correlation.
Diègo LEGROS, Myriam ABDELMOULA
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
URBAN STRUCTURE: ITS ROLE IN URBAN GROWTH, NET NEW BUSINESS FORMATION AND INDUSTRIAL CHURN [PDF]
Cities are the “engines of growth” because entrepreneurial and cre-ative activities are concentrated in cities. This suggests that cities grow by host-ing new businesses and “churning” industries advantageously.
Bumsoo LEE, Peter GORDON
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Front Matter Vol. 18 No.2 (2023)
Region: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023 Jurnal Region
doaj
Regional determinants of residential energy expenditures and the principal-agent problem in Austria
REGION, 2015 The aim of this paper is two-fold: 1) to examine the determinants of residential energy expenditures and compare them on a regional level; and, 2) attempt to identify and measure the effect of possible principal-agent (PA) problems on residential energy ...
Daniel R. Hill
doaj
ON THE RELATIONSHIPS BETWEEN SPATIAL CLUSTERING, INEQUALITY, AND ECONOMIC GROWTH IN THE UNITED STATES : 1969-2000 [PDF]
The literature on economic development has been divided as to the nature of the relationship between inequality and growth. Recent exploratory work in the field has provided evidence that the dynamic and spatial relationships between the two may be far ...
Mark V. JANIKAS, Sergio J. REY
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source