Results 61 to 70 of about 14,433,678 (306)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

REAT: A Regional Economic Analysis Toolbox for R

open access: yesREGION, 2019
Methods of regional economic analysis are widely used in regional and urban economics as well as in economic geography. This paper introduces the REAT (Regional Economic Analysis Toolbox) package for the programming environment R, which provides a ...
Thomas Wieland
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Front Matter Vol. 18 No.1 (2023)

open access: yesRegion: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023
Jurnal Region
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Back Matter Vol. 18 No.1 (2023)

open access: yesRegion: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023
Jurnal Region
doaj   +1 more source

An Overview of Urbanization in Ecuador under Functional Urban Area Definition

open access: yesREGION, 2018
This paper explores the urbanization process under Functional Urban Areas (FUAs) definition considering Ecuador as case of study. Analyzing data from 1950 to 2010, we have identified 28 FUAs that confirm that urbanization has rapidly increased in Ecuador
Moises Obaco Alvarez   +1 more
doaj   +1 more source

EDUCATIONAL PERFORMANCE AND SPATIAL CONVERGENCE IN PERU [PDF]

open access: yes
While an enormous and growing literature exists on the topic of re-gional income convergence, other aspects of socioeconomic well-being and development have attracted much less attention. Social indicators are a valuable complement to economic indicators
Maribel ELIAS, Sergio J. REY
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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