Results 61 to 70 of about 9,092,180 (307)
Annual Report for 1956 on the working of The Public Service Commission Western Region, Nigeria. [PDF]
, 1957 The aim of this Government is to build up and maintain in this Region an efficient and contented Civil Service. This first Report on the Regional Public Service Commission. We have sought to give not only a complete picture of its working during the year
WESTERN REGION OF NIGERIA
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Theoretical Computer Science, 2017 In this paper we present a brief overview of a representative fragment of the theory of regions. Regions are a powerful tool for the synthesis of concurrent systems from a behavioural specification. To demonstrate the robustness of region based synthesis we survey some of the existing results for extensions of place/transition nets.
Kleijn J +3 more
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Towards A Regional Science Academy: A Manifesto
REGION, 2016 This Manifesto provides a joint proposal to create a Regional Science Academy as a think-tank support platform for a strategic development of the spatial sciences.
Karima Kourtit, Peter Nijkamp
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
séminaire la contribution de la société civile dans la lutte contre l'impunité dans la region des Grands Lacs [PDF]
, 2008 Document collected by the University of Texas Libraries from the web-site of the Reseau Documentaire International Sur La Region Des Grands Lacs Africains (International Documentation Network on the Great African Lakes Region).
LIGUE DES DROITS DE LA PERSONNE DANS LA REGION DES GRANDS LACS ( L.D.G.L.) +1 more
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REGION, 2019 Today, Mediterranean marginal territories are facing tremendous challenges but at the same time they have relevant endogenous resources, which are often underutilized and unexploited and that could be pivotal for the strategic recovery and economic and ...
Andrea Ricci +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source