Nerves and Anesthesia: A physics perspective on medicine [PDF]
We present a recent theory for nerve pulse propagation and anesthesia and argue that both nerve activity and the action of anesthetics can be understood on the basis of simple physical laws. It was found experimentally that biological membranes melt from a solid state to a liquid state just below physiological temperature. Such melting processes have a
arxiv
Hysteresis in anesthesia and recovery: Experimental observation and dynamical mechanism [PDF]
The dynamical mechanism underlying the processes of anesthesia-induced loss of consciousness and recovery is key to gaining insights into the working of the nervous system. Previous experiments revealed an asymmetry between neural signals during the anesthesia and recovery processes.
arxiv
Controlling the Error on Target Motion through Real-time Mesh Adaptation: Applications to Deep Brain Stimulation [PDF]
We present an error-controlled mesh refinement procedure for needle insertion simulation and apply it to the simulation of electrode implantation for deep brain stimulation, including brain shift. Our approach enables to control the error in the computation of the displacement and stress fields around the needle tip and needle shaft by suitably ...
arxiv +1 more source
Prediction of Individual Propofol Requirements based on Preoperative EEG Signals [PDF]
The patient must be given an adequate amount of propofol for safe surgery since overcapacity and low capacity cause accidents. However, the sensitivity of propofol varies from patient to patient, making it very difficult to determine the propofol requirements for anesthesia.
arxiv
Perioperative blood loss and diclofenac in major arthroplastic surgery [PDF]
Introduction: Contemporary literature indicates precaution over the perioperative use of non-steroidal anti-inflammatory drugs, since they can potentially increase perioperative blood loss related to their mechanism of action.
Gojković, Zoran+4 more
core +3 more sources
Quantification of depth of anesthesia by nonlinear time series analysis of brain electrical activity [PDF]
We investigate several quantifiers of the electroencephalogram (EEG) signal with respect to their ability to indicate depth of anesthesia. For 17 patients anesthetized with Sevoflurane, three established measures (two spectral and one based on the bispectrum), as well as a phase space based nonlinear correlation index were computed from consecutive EEG
arxiv +1 more source
Post-operative cognitive function following general versus regional anesthesia, a systematic review [PDF]
The effect of anesthetic technique on postoperative outcomes remains in question. This systematic review compares the role of regional versus general anesthesia, with a particular focus on postoperative cognitive function.
Davis, Nicholas+7 more
core +2 more sources
Structure and Dynamics of Brain Lobe's Functional Networks at the Onset of Anesthesia-Induced Loss of Consciousness [PDF]
Anesthetic agents are neurotropic drugs capable of inducing significant alterations in the thalamocortical system, promoting a profound decrease in awareness and level of consciousness. There is experimental evidence that general anesthesia affects large-scale functional networks, leading to alterations in the brain's state.
arxiv
Pregnancies complicated by maternal osteogenesis imperfecta type III: a case report and review of literature. [PDF]
The restrictive lung disease can be exacerbated by growing fundus in women with osteogenesis imperfecta type III. Regional anesthesia can be performed in these women.
Al-Kouatly, Huda B.+3 more
core +1 more source
Characterization of Large-Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction [PDF]
Several experiments provide evidence that specialized brain regions functionally interact and reveal that the brain processes and integrates information in a specific and structured manner. Networks can be applied to model brain functional activities, providing means to characterize and quantify this structured form of organization.
arxiv