Results 61 to 70 of about 3,520,550 (310)

An Engineered Thio‐Amino Polymer Achieves Potent, Safe, and Broad Cell Type Delivery in the Lung Mapped by Spatial Transcriptomics

Advanced Materials, EarlyView.
Synthesis and screening of a polymer library produced a versatile and inhalable mRNA vehicle for the lungs (P81). Compared to a published LNP, P81 provides increased delivery efficacy, achieving widespread expression in broad cell types, with no toxicity.
Pramodkumar EK, Younghun Jung, Elex S. Rose, Jae Yeon Joo, James R. Rose, José A. F. Assumpção, Hyeyoon Jeong, Lorena C. S. Chaves, Blake Andrew Miller, João Paulo Pera Mendes, Hannah E. Peck, Charmy J. Patel, Loren E. Sasser, Heather Pathak, Varun V. Mosur, Jaehyeon Hwang, Guilherme de Oliveira Lopes, Merrilee Thoresen, Santiago Cornejo, Peres Badial, Alicia Olivier, Amelia R. Woolums, Samuele Stazzoni, Noemi Manganaro, Eleonora Nencini, Giulio Pierleoni, Emanuele Andreano, Rino Rappuoli, Nichole Orr‐Burks, Sarah R. Hosking, Nicholas S. Heaton, Eric R. Lafontaine, Robert J. Hogan, Francois Villinger, Daryll Vanover, Chiara Zurla, Philip J. Santangelo   +36 more
wiley   +1 more source

Cardiac arrest in a child during a combined general epidural anesthesia procedure [PDF]

, 2005
An increased risk of perioperative cardiac arrest in children, in comparison to adults, has been recognized. A number of factors associated with perioperative cardiac arrest have been identified, including young age, comorbidities, and emergency ...
Soenarjo, Soenarjo, Soemantri,, A, Sidhartani,, M, Siahaan, Edwin MP, Prabakti, Yudhi   +4 more
core   +1 more source

REGIONAL ANESTHESIA FOR OBSTETRICS

Anesthesiology Clinics of North America, 2000
The practice of administration of labor analgesia has undergone dramatic changes this decade. This is largely attributable to unparalleled interest in the field by many dedicated and capable investigators around the world. Through their efforts, this decade has witnessed the introduction of new techniques (pencil point needles, CSE, PCEA, ultradilute ...
openaire   +2 more sources

3D Printed Photon Shield Assembly for Low‐Noise Visual Stimulation During Two‐Photon Imaging in Mice

Advanced Materials Technologies, EarlyView.
We present the Photon Shield, an open‐hardware system for low‐noise two‐photon calcium imaging during visual stimulation in mice. Combining a 3D‐printed headplate and rail‐mounted shield substantially reduces stray‐light contamination, as quantitatively verified. Functional validation confirms reliable cortical responses. Open design files enable broad
Gergely Katona, Andrea Slézia, András Dávid, Ábel Petik, Dániel Hillier, István Ulbert, Attila Kaszás   +6 more
wiley   +1 more source

Recent advances in intravenous anesthesia and anesthetics [version 1; referees: 2 approved]

F1000Research, 2018
Anesthesiology, as a field, has made promising advances in the discovery of novel, safe, effective, and efficient methods to deliver care. This review explores refinement in the technology of soft drug development, unique anesthetic delivery systems, and
Mohamed Mahmoud, Keira P. Mason
doaj   +1 more source

Local and Regional Anesthesia: Clinical Considerations

, 2022
Local and regional anesthesia, in discrepancy to systemic, general anesthesia, involves the reversible deadening of a specific region of the body to help any sensation of pain.
Héctor Zúñiga- Gazcón, Diego Eduardo Saavedra Mayorga, Félix Osuna Gutiérrez, Jorge Eduardo Escobedo Arriazola, Myrna Lizeth Cuevas Meléndez, Miguel Angel Flores Delgado   +5 more
core   +1 more source

Toward Perception‐Native Electronic Skin: Bio‐Inspired In‐/Near‐Sensor and Neuromorphic Computing for Humanoid Robots

Advanced Materials Technologies, EarlyView.
Dense tactile streams from across the humanoid body converge on collide in a central wiring and data bottleneck. By relocating computation closer to and then into the skin itself, near‐ and in‐sensor architectures, together with neuromorphic computing, chart a path toward perception‐native electronic skin, in which the conversion of stimulus into ...
Mijin Kim, Chang‐Jae Beak, Jiyoung Park, Youngdo Jung, Sunjong Oh, Sin‐Hyung Lee, Bo‐Yeon Lee   +6 more
wiley   +1 more source

Nonoperating room regional anesthesia in pediatric patients: A review of indications and challenges

Journal of Indira Gandhi Institute of Medical Sciences
Nonoperating room regional anesthesia (NORRA) involves providing regional anesthesia in environments other than the standard operating rooms, such as in intensive care units, emergency departments, or interventional radiology suites.
Vikram Chandra, Amarjeet Kumar, Chandni Sinha, Ajeet Kumar   +3 more
doaj   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Comparing Alteration of MMSE (Mini-Mental State Examination) Scores as Cognitive Function Test in Geriatrics After General and Regional Anesthesia

Indonesian Journal of Anesthesiology and Reanimation (IJAR), 2020
Introduction: An alteration of cognitive function in geriatrics often occurred after a surgery procedure. To do a surgery, patients would go through the process with anesthesia, whether it is  general or regional anesthesia.
Ferrie Budianto, Philia Setiawan, Hamzah Hamzah, Erikavitri Yulianti   +3 more
doaj   +1 more source