Results 71 to 80 of about 3,847 (216)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Use of levobupivacaine in carotid endarterectomy

Трансплантология (Москва)
Background. Аnesthesia for carotid endarterectomy can be used as a combined endotracheal anesthesia, regional anesthesia, and also a combination of combined endotracheal anesthesia with regional anesthesia.
S. V. Zhuravel, N. K. Kuznetsova, E. A. Korotkova, S. A. Mustafayeva, N. S. Dolgasheva, I. P. Mikhailov   +5 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Efficacy and safety of multimodal analgesic techniques for preventing chronic postsurgery pain under different surgical categories: a meta-analysis

Scientific Reports, 2017
The purpose of this meta-analysis was to compare the efficacy and safety of regional anesthesia to manage chronic postsurgery pain. A systematic search of PubMed, EmBase, and the Cochrane Central Register of Controlled Trials was performed to identify ...
Jun Zhou, Youling Fan, Jiying Zhong, Xianjie Wen, Hongtao Chen   +4 more
doaj   +1 more source

Factors affecting selection of anesthesia type in elective cesarean operations and pregnant preferences for anesthesia outcome

Medicine Science, 2019
The aim of study is to determine the factors having an effect on the selections of anesthesia type for the pregnant. The research was performed on 274 female patients, who applied to Antalya Research Training and Research Hospital within a 2-months ...
Baris Arslan, Nilgun Kavrut Ozturk, Zinet Asuman Arslan Onuk, Bilge Karsli   +3 more
doaj   +1 more source

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

Advanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu, Haitao Gao, Qingyang Liu, Sishen Yuan, Haiyang Fang, Mingwu Su, Baijia Liang, Yongzun Yang, Long Bai, Wenzhen Dong, Dihong Xie, Shijian Su, Jiewen Lai, Shing Shin Cheng, Zhen Li, Xiuli Zuo, Hongliang Ren   +16 more
wiley   +1 more source

Safety of Cubital Tunnel Release Under General versus Regional Anesthesia

Local and Regional Anesthesia, 2023
Courtney R Carlson Strother,1 Lauren E Dittman,1 Marco Rizzo,1 Steven L Moran,2 Peter C Rhee1 1Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; 2Department of Plastic Surgery, Mayo Clinic, Rochester, MN, USACorrespondence: Peter C Rhee,
Carlson Strother CR, Dittman LE, Rizzo M, Moran SL, Rhee PC   +4 more
doaj  

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Effect of Regional Versus Local Anesthesia on Outcomes of Radiocephalic Arteriovenous Fistula Creation for Hemodialysis Access: A Prospective Randomized Study

Kardiyovasküler Tıp E Dergisi/E Journal of Cardiovascular Medicine
Objectives: To investigate the effect of regional versus local anesthesia on perioperative outcomes in patients with end-stage renal disease undergoing radiocephalic arteriovenous fistula for hemodialysis access.
Mustafa Selçuk Atasoy, Hakan Güven, Ahmet Yüksel, Ayhan Müdüroğlu, Demir Çetintaş, Ali Önder Kılıç, Serdar Badem, Mustafa Aldemir, Mustafa Çağdaş Çayır, Murad Kaya, Mustafa İşleyen, Yusuf Velioğlu   +11 more
doaj   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source