Results 161 to 170 of about 616,798 (355)
Advanced Science, EarlyView.By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao +14 more
wiley +1 more source
Effects of nicotine on odor-induced increases in regional blood flow in the olfactory bulb in rats. [PDF]
J Physiol Sci, 2019 Uchida S, Ito Y, Kagitani F.
europepmc +1 more source
The effect of haemorrhage on venous return and regional blood flow in the anaesthetized cat
, 1966 C. V. Greenway, Anne E. Lawson
openalex +2 more sources
Effects of Nitroglycerin on Regional Myocardial Blood Flow in Coronary Artery Disease [PDF]
, 1971 Lawrence D. Horwitz +3 more
openalex +1 more source
Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
Advanced Science, EarlyView.Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou +18 more
wiley +1 more source
Effects of GIP on regional blood flow during normoglycemia and hyperglycemia in anesthetized rats. [PDF]
Physiol Rep, 2018 Gao X +5 more
europepmc +1 more source
Advanced Science, EarlyView.This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang +19 more
wiley +1 more source
A study of physiological mechanisms and inter-relations between systemic and regional blood volume, blood flow and electrolyte balance Interim progress report, Jun. 30 - Dec. 31, 1967 [PDF]
Regulation of sodium excretion in dog, and effects of atrial size and function upon secretion of sodium load - circulatory response to upright ...
Abelmann, W. H., Earley, L. E.
core +2 more sources
Advanced Science, EarlyView.This study presents an engineered probiotic platform, iRGD‐mRBC@FOLactis, combining red blood cell membrane cloaking and tumor‐penetrating peptide iRGD for enhanced PD‐1 blockade. The platform improves tumor targeting, immune cell activation and therapeutic efficacy in lung cancer, demonstrating significant promise in overcoming PD‐1/PD‐L1 therapy ...
Chen Chen +9 more
wiley +1 more source