MRI Epicenters Differentiate Spatiotemporal Patterns of Neurodegeneration in Parkinson's Disease
A connectivity‐based MRI epicenter model identifies two Parkinson's disease subtypes: subtype 1 with infratentorial‐dominant epicenters, severe motor symptoms, and rapid progression; and subtype 2 with supratentorial‐dominant epicenters with mild progression.
Xiaojie Duanmu +23 more
wiley +1 more source
Energy availability modulates regional blood flow via estrogen-independent pathways in regularly menstruating young women. [PDF]
Hutson MJ +4 more
europepmc +1 more source
Discussion of “Regional Adjustments of Intestinal Blood Flow”
Benjamin W. Zweifach
openalex +1 more source
A novel, wearable anti‐cancer platform synergistically combines tumor treating fields (TTFs) and piezocatalytic therapy (PCT) via ultrasound‐activated, lead‐free piezocomposites. This strategy efficiently suppresses tumor growth, modulates the immune microenvironment, and demonstrates strong therapeutic synergy in both mouse model of subcutaneous tumor
Jing Jin +9 more
wiley +1 more source
EFFECTS OF ATENOLOL ON REGIONAL MYOCARDIAL BLOOD FLOW AND ST SEGMENT ELEVATION IN THE CANINE MYOCARDIUM [PDF]
Alain Berdeaux +2 more
openalex +1 more source
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu +11 more
wiley +1 more source
Can Plasma Skimming or Inconstancy of Regional Hematocrit Introduce Serious Errors in Regional Cerebral Blood Flow Measurements or Their Interpretation? [PDF]
William I. Rosenblum
openalex +1 more source
Parabiosis, Assembloids, Organoids (PAO)
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source
Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes. [PDF]
Hill RA +5 more
europepmc +1 more source

