Results 71 to 80 of about 1,043,640 (304)

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

A Statistical Model for Regional Tornado Climate Studies

PLOS ONE, 2015
Tornado reports are locally rare, often clustered, and of variable quality making it difficult to use them directly to describe regional tornado climatology. Here a statistical model is demonstrated that overcomes some of these difficulties and produces a smoothed regional-scale climatology of tornado occurrences.
Thomas H Jagger, James B Elsner, Holly M Widen   +2 more
openaire   +4 more sources

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Future Climate in the Tibetan Plateau from a Statistical Regional Climate Model [PDF]

Journal of Climate, 2013
Abstract The authors use a statistical regional climate model [Statistical Regional Model (STAR)] to project the Tibetan Plateau (TP) climate for the period 2015–50. Reanalysis datasets covering 1958–2001 are used as a substitute of observations and resampled by STAR to optimally fit prescribed linear temperature trends derived from the ...
Zhu, X., Wang, W., Fraedrich, K.
openaire   +2 more sources

Global and Regional Marine Ecosystem Models Reveal Key Uncertainties in Climate Change Projections

Earth's Future
Climate change is affecting ocean temperature, acidity, currents, and primary production, causing shifts in species distributions, marine ecosystems, and ultimately fisheries.
Tyler D. Eddy, Ryan F. Heneghan, Andrea Bryndum‐Buchholz, Elizabeth A. Fulton, Cheryl S. Harrison, Derek P. Tittensor, Heike K. Lotze, Kelly Ortega‐Cisneros, Camilla Novaglio, Daniele Bianchi, Matthias Büchner, Catherine Bulman, William W. L. Cheung, Villy Christensen, Marta Coll, Jason D. Everett, Denisse Fierro‐Arcos, Eric D. Galbraith, Didier Gascuel, Jerome Guiet, Steve Mackinson, Olivier Maury, Susa Niiranen, Ricardo Oliveros‐Ramos, Juliano Palacios‐Abrantes, Chiara Piroddi, Hubert duPontavice, Jonathan Reum, Anthony J. Richardson, Jacob Schewe, Lynne Shannon, Yunne‐Jai Shin, Jeroen Steenbeek, Jan Volkholz, Nicola D. Walker, Phoebe Woodworth‐Jefcoats, Julia L. Blanchard   +36 more
doaj   +1 more source

PROJECTED PRECIPITATION CHANGES IN CENTRAL/EASTERN EUROPE ON THE BASIS OF ENSEMBLE SIMULATIONS [PDF]

Aerul şi Apa: Componente ale Mediului, 2012
Projected precipitation changes in Central/Eastern Europe on the basis of ENSEMBLE simulations. For building appropriate local/national adaptation and mitigation strategies, detailed analysis of regional climate change is essential.
Erika Miklos, Rita Pongracz, Judit Bartholy, Anna Kis   +3 more
doaj  

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

A coupled regional climate-biosphere model for climate studies [PDF]

, 1996
This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The objective of this project has been to develop and test a regional climate modeling system that couples a limited-area atmospheric code to a biosphere scheme that properly represents surface processes ...
Bossert, J., Winterkamp, J., Barnes, F., Roads, J.   +3 more
openaire   +2 more sources

Role of climate model dynamics in estimated climate responses to anthropogenic aerosols [PDF]

Atmospheric Chemistry and Physics, 2019
Significant discrepancies remain in estimates of climate impacts of anthropogenic aerosols between different general circulation models (GCMs). Here, we demonstrate that eliminating differences in model aerosol or radiative forcing fields results in ...
K. Nordling, H. Korhonen, P. Räisänen, M. E. Alper, P. Uotila, D. O'Donnell, J. Merikanto   +6 more
doaj   +1 more source

Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China

Advanced Science, EarlyView.
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng, Wei Li, Philippe Ciais, Martin Brandt, Xiaowei Tong, Yanzheng Yang, Guofeng Shen, Wei Du, Lei Zhu, Yi Leng, Minxuan Sun, Mengjie Han, Xuemei Zhang, Jie Zhang, Nan Wang, Dan Tong, Chao Wu, Wenhao Dong, Shu Tao, Bo Pan   +19 more
wiley   +1 more source