Results 21 to 30 of about 9,187 (121)

Global and Regional Left Ventricular Contractile Impairment In Patients With Wolff-Parkinson-White Syndrome

Indian Pacing and Electrophysiology Journal, 2009
Background: To assess regional systolic function and global contractile function in patients with WPW Syndrome.Method: Eleven cases with manifest Wolff-Parkinson-White (WPW) syndrome in sinus rhythm were compared to 11 age matched controls.
Sony Jacob, Ashutosh Niraj, Vikas Veeranna, Jyotiranjan Pradhan, Luis Afonso   +4 more
doaj  

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

POSTNATAL REMODELING OF THE MYOFIBRILLAR APPARATUS IN TYPICAL RAT CARDIOMYOCYTES AFTER EXPOSURE TO CHRONIC PRENATAL HYPOXIA

Проблеми екології та медицини
Introduction. Chronic prenatal hypoxia is a significant factor affecting the development of the fetal myocardium, particularly the formation and remodeling of the myofibrillar apparatus in cardiomyocytes.
I.V. Tverdokhlib, P.A. Kobeza
doaj   +1 more source

Congenital Myopathies and Muscular Dystrophies: A Single Tertiary Center Experience and Factors Associated With Long‐Term Outcomes

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Data on respiratory, feeding, ambulatory outcomes and prognostic factors for congenital myopathies (CM) and congenital muscular dystrophies (CMD) remain limited. Therefore, in this study, we report the characteristics of a large single‐center cohort of patients with CM and CMD, focusing on long‐term outcomes and aiming to ...
Can Ozlu, Margaret McGurn, Susan Iannaccone, Zurisadai Gonzalez Castillo, Kaitlin Batley   +4 more
wiley   +1 more source

Non-ischemic phenotypes of low-risk chest pain patients based on exercise stress echocardiography: a pilot study

Frontiers in Cardiovascular Medicine
ObjectiveA significant proportion (∼85%) of low-risk non-ST-elevation acute coronary syndrome (NSTE-ACS) patients do not receive objective confirmation of ischemia by stress echocardiography (SE), yet remain a healthcare burden due to lower long-term ...
Tamara Ryabova, Elena Abramenko, Ivan Yolgin, Konstantin Zavadovsky, Vyacheslav Ryabov   +4 more
doaj   +1 more source

Single‐nucleotide polymorphisms in coronary artery disease: Biological complexity, risk architecture, and implications for precision prevention

Precision Medical Sciences, EarlyView.
This graphical summary highlights the clinical application of single‐nucleotide polymorphisms‐based risk stratification in coronary artery disease. By integrating polygenic risk with clinical assessment, imaging, and preventive strategies, genetic information enables earlier risk identification, optimized screening, and personalized lifestyle and ...
Li Dai, Mosi Chen, Jun Hu, Lei Huang, Ye Yang, Chang Chen, Ying Zhuang, Yan Pan, Bingjun Qian   +8 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Novel cardiovascular magnetic resonance strain heterogeneity phenotypes predict cardiovascular events: A prospective UK Biobank study

Journal of Cardiovascular Magnetic Resonance
: Background: Global longitudinal (GLS), circumferential (GCS) and radial (GRS) strains may be insufficiently sensitive to early regional pathological cardiac remodeling on cardiovascular magnetic resonance imaging (CMR).
Kerrick Hesse, Mohammed Y. Khanji, C. Anwar A. Chahal, Sucharitha Chadalavada, Kenneth Fung, Jose D. Vargas, Jose Paiva, Steffen E. Petersen, Nay Aung   +8 more
doaj   +1 more source

Exploring the Passive Second Stage of Labour and Related Perinatal Outcomes in a Physiological Cohort

Birth, EarlyView.
ABSTRACT Background The passive second stage of labor has been increasingly recognized as a normal phase of labor. However, it remains poorly studied, especially in healthy women. This study aims to assess the passive phase in healthy laboring women and maternal and neonatal outcomes.
Lucia Zagra, Maria Panzeri, Simona Fumagalli, Teresa Gramegna, Antonella Nespoli, Sara Ornaghi, Anna Locatelli   +6 more
wiley   +1 more source