Results 21 to 30 of about 9,474 (137)
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Проблеми екології та медициниIntroduction. Chronic prenatal hypoxia is a significant factor affecting the development of the fetal myocardium, particularly the formation and remodeling of the myofibrillar apparatus in cardiomyocytes.
I.V. Tverdokhlib, P.A. Kobeza
doaj +1 more source
Pediatric Cardiac Function Staging and Management Recommendations
Pediatric Discovery, EarlyView.ABSTRACT The global prevalence of heart failure in children continues to increase, accompanied by a growing disease burden. To advance early prevention and intervention by shifting the focus upstream in the disease process, the Cardiovascular Group of the Pediatrics Society of the Chinese Medical Association has introduced the concept of pediatric ...
Bo Pan +21 more
wiley +1 more source
Frontiers in Cardiovascular MedicineObjectiveA significant proportion (∼85%) of low-risk non-ST-elevation acute coronary syndrome (NSTE-ACS) patients do not receive objective confirmation of ischemia by stress echocardiography (SE), yet remain a healthcare burden due to lower long-term ...
Tamara Ryabova +4 more
doaj +1 more source
Allergy, EarlyView.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
Birth, EarlyView.ABSTRACT Background The passive second stage of labor has been increasingly recognized as a normal phase of labor. However, it remains poorly studied, especially in healthy women. This study aims to assess the passive phase in healthy laboring women and maternal and neonatal outcomes.
Lucia Zagra +6 more
wiley +1 more source
Journal of Cardiovascular Magnetic Resonance: Background: Global longitudinal (GLS), circumferential (GCS) and radial (GRS) strains may be insufficiently sensitive to early regional pathological cardiac remodeling on cardiovascular magnetic resonance imaging (CMR).
Kerrick Hesse +8 more
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British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
The FEBS Journal, EarlyView.Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
Journal of Small Animal Practice, EarlyView.Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon +3 more
wiley +1 more source