Results 51 to 60 of about 9,477 (127)
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.SRM 1650b diesel particulate matter caused dose‐dependent cardiotoxicity in isolated male Wistar rat hearts, worsening hemodynamics and tissue injury after ischemia–reperfusion. It increased oxidative stress, impaired mitochondrial bioenergetics and respiration, downregulated mitochondrial quality‐control genes, reduced mtDNA copy number, and ...
Kirankumar Balu +4 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background Musculoskeletal complications in type 2 diabetes (T2DM) are inadequately captured by body mass index (BMI). Waist‐to‐BMI ratio (WBR) may better reflect adverse body composition. We examined cross‐sectional and longitudinal associations between WBR and musculoskeletal disorders in T2DM.
Yongze Zhang +8 more
wiley +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Lymphatic Endothelial Cells in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang +5 more
wiley +1 more source
Characterizing Metabolic and Compositional Heterogeneity of Calf Muscle Using CEST MRI at 3 T
NMR in Biomedicine, Volume 39, Issue 8, August 2026.This study used 3 T CEST MRI to characterize metabolic and compositional heterogeneity in eight healthy calf muscles, focusing on amide, PCr, rNOE, and MT contrasts. Distinct signatures emerged between deep stabilizer and superficial powerhouse muscles. Significant correlations with age, fat content, BMI, and strength (e.g., rNOE vs. strength) revealed
Huabin Zhang +10 more
wiley +1 more source
Echocardiography, Volume 43, Issue 8, August 2026.After septal myectomy for hypertrophic obstructive cardiomyopathy, the four chambers of the heart experience unique remodeling patterns that can be visualized with speckle‐tracking strain analysis on echocardiography. This study characterizes those changes and links them to clinical outcomes such as post‐operative atrial fibrillation risk, thereby ...
Olga N. Kislitsina +10 more
wiley +1 more source
Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review
European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino +9 more
wiley +1 more source
Journal of Small Animal Practice, Volume 67, Issue 8, Page 663-679, August 2026.Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon +3 more
wiley +1 more source
Experimental Physiology, Volume 111, Issue 8, Page 3570-3587, 1 August 2026.Abstract Prolonged physical inactivity alters the cardiovascular system, including the heart. Long‐term bed rest is known to decrease left ventricular volume and cause diastolic dysfunction; however, the interplay between these changes and their effect on cardiac contractility have been understudied.
Jérémy Rabineau +9 more
wiley +1 more source
Brain sparing in fetal growth restriction: The double‐edged sword of fetal hypoxaemia
The Journal of Physiology, Volume 604, Issue 15, Page 6259-6280, 1 August 2026.Abstract figure legend The double‐edged sword of brain sparing. Fetal hypoxaemia triggers a coordinated adaptive response characterised by redistribution of cardiac output toward essential organs, including the brain, and a reduction in overall metabolic activity to preserve oxygen supply.
Beth J. Allison +3 more
wiley +1 more source