Results 181 to 190 of about 529,537 (309)

Structural Insights Into Man9 Recognition by the HIV Antibody 2G12 Revealed by Paramagnetic NMR

open access: yesAdvanced Science, EarlyView.
The HIV gp120 glycoprotein displays Man9 oligomannose structures that are recognized by the neutralizing antibody 2G12. Detailed characterization of the binding epitope in solution is important for immunogen design but remains challenging, since the signals of the terminal mannoses from the three arms of Man9 (D1, D2, and D3) cannot be distinguished in
Adrián Silva‐Díaz   +7 more
wiley   +1 more source

Regional convergence of output per worker in China : a neoclassical interpretation. [PDF]

open access: yes
Regional output per worker has converged across Chinese provinces in 1979- 1989. The estimated rate of convergence is 2.2 percent. This rate of convergence can be explained by neoclassical growth model conditional on assumptions about factor mobility and
Gundlach, Erich
core  

From Cell‐Free Transcriptomes to Single‐Cell Landscapes: Biomarker Discovery and Originating Cell Alteration Analysis via Graph Matrix Factorization

open access: yesAdvanced Science, EarlyView.
CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang   +9 more
wiley   +1 more source

Determinants of regional productivity growth in Europe: an empirical analysis [PDF]

open access: yes
Discussion on the possibilities for and barriers to income convergence and catch-up growth is at the heart of the debate on European regional economic policy.
Ferdinand Paraguas   +3 more
core  

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

open access: yesAdvanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang   +11 more
wiley   +1 more source

Multiple Regimes in Cross-Region Growth Regressions with Spatial Dependence: A Parametric and a Semi-parametric Approach [PDF]

open access: yes
This paper studies the distribution dynamics of development across European regions over the period 1975-2000. Regional development is measured in terms of both per capita GDP (Y/P) and its components: labour productivity and employment ratio (that in ...
Luca De Benedictis   +3 more
core  

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

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