Results 61 to 70 of about 1,283,135 (288)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impacts of different levels of urban expansion on habitats at the regional scale and their critical distance thresholds

Environmental Research Letters, 2023
With the rapid development of urbanization, natural habitats in many parts of the world have been seriously damaged by urban expansion. However, urban expansion is a complex process, and the impacts of different levels of urban expansion on habitats at ...
Shuaipeng Chen, Wenping Liu
doaj   +1 more source

starbench: the D-type expansion of an H ii region [PDF]

Monthly Notices of the Royal Astronomical Society, 2015
20 pages, 12 Figures, 4 Tables. Accepted for publication in MNRAS. Comments are welcome.
Bisbas, T., Haworth, J., Williams, R., Mackey, J., Tremblin, Pascal, Raga, C., Arthur, S., Baczynski, C., Dale, J., Frostholm, T., Geen, S., Haugbølle, T., Hubber, D., Iliev, I., Kuiper, R., Rosdahl, J., Sullivan, D., Walch, S., Wünsch, R.   +18 more
openaire   +6 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Indonesia’s Plan for Concurrent Regional Expansion

IOP Conference Series: Earth and Environmental Science, 2023
Abstract The development of ties between the center and the regions came to light after Indonesia underwent reformation in 1998. A new paradigm in the management of local government in Indonesia has emerged as a result of the passing of Law No. 22 of 1999. One effect of the passage of Law No.
openaire   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Geomorphology and Hydroclimate Control Regional Urban Expansion

Earth's Future
The scale of urbanization is well‐acknowledged and future projections outline severe sustainability concerns. Existing studies acknowledge that several environmental, hydroclimatic, socioeconomic, policy, and institutional factors control urban growth ...
Serena Ceola, Giulia Grandi, Enrico Bertuzzo   +2 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

The upswing of regional income inequality in Spain (1860–1930). [PDF]

This paper studies the evolution of Spanish regional inequality from 1860 to 1930. The results point to the coexistence of two basic forces behind changes in regional economic inequality: industrial specialization and labor productivity differentials ...
Martínez-Galarraga, Julio, Rosés, Joan R., Tirado, Daniel A.   +2 more
core   +3 more sources