Results 141 to 150 of about 342,486 (260)
Advanced Science, EarlyView.Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner +14 more
wiley +1 more source
Advanced Science, EarlyView.Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke +14 more
wiley +1 more source
Mapping Local and Regional Potentials for Inter-sectoral Technology Flows in Industrial Clusters – Empirical Results for Germany [PDF]
The paper explores the potential for inter-sectoral technology flows in industrial clusters in Germany. With the help of a product-embodied R&D flow matrix, calculated using data on input–output tables and sectoral R&D employment, we construct industrial
Hans-Ulrich Brautzsch +2 more
core
Scalable Electrochemical Concrete Fabrication and Closed‐Loop Recycling
Advanced Science, EarlyView.The electrochemical‐driven recycling strategy establishes a reversible concrete material flow by extracting Ca, Si, Al, and Fe from concrete waste and regenerating functional feedstocks. These reversed products are reassembled into new concrete, which re‐enters service and ultimately returns to waste, enabling a closed‐loop, waste‐origin, and low ...
Hanxiong Lyu +7 more
wiley +1 more source
Spatial projection of input-ouput tables for small areas [PDF]
Studies on regional economy have achieved a huge expansion in the last decades. In particular, from an input-ouput optic many efforts have been devoted to carring out a suitable methodology, which enable us to cover the overall and exhaustive knowledge ...
Alvarez Herrero, Ruben +2 more
core
Advanced Science, EarlyView.CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang +9 more
wiley +1 more source
Distinct Biotypes of Visual Perception in Major Depressive Disorder
Advanced Science, EarlyView.In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai +13 more
wiley +1 more source
International Trade in Intermediate Inputs: The Case of the Automobile Industry [PDF]
International trade statistics and input-output tables are analyzed in order to test the hypothesis that international production networks have become more relevant. The share of imported inputs in the gross output value of the motor vehicle industry has
Markus Diehl
core
Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle
Advanced Science, EarlyView.Using fiber photometry and genetically encoded sensors, the dynamic release patterns of four neuromodulators in the olfactory tubercle (OT)—a brain region overlapping with the olfactory cortex and ventral striatum—were systematically monitored in response to external rewards and distinct reward‐associated learning processes.
Maojun Hong +7 more
wiley +1 more source
A non-survey estimation for regional input-output tables. An application for Buenos Aires City. [PDF]
The input output analysis is used by a lot of cities with the objective to study interregional trade problems. We focused our work on Argentina, and we present a model with two regions: Buenos Aires city and the rest of the country. Buenos Aires does not
Mastronardi, Leonardo Javier +1 more
core +1 more source