Results 31 to 40 of about 22,936 (216)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

An inter-regional input-output table series of China from 1987–2017 with integrated carbon emission data

open access: yesScientific Data
Inter-regional input-output (IRIO) tables are essential for socioeconomic and environmental analysis. This paper compiled a continuous time series of Chinese IRIO tables with a detailed regional and sectoral classification, covering a longer period from ...
Qiong Zhao   +6 more
doaj   +1 more source

Does consistency with detailed national data matter for calculating carbon footprints with global multi-regional input–output tables? A comparative analysis for Belgium based on a structural decomposition

open access: yesJournal of Economic Structures, 2018
Consistency with detailed national data is an important challenge when using multi-regional input–output (MRIO) tables for carbon footprint analysis at the national level.
Caroline Hambÿe   +2 more
doaj   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad   +22 more
wiley   +1 more source

Development of regional input-output tables for Northern Ghana: An analysis using location quotient methods

open access: yesCogent Social Sciences
We developed regional input–output tables for Northern Ghana using the latest 2018 national input-output table for Ghana and the 2021 Ghana population and housing census data.
Kwabena Asomanin Anaman   +1 more
doaj   +1 more source

National and regional effects of RCEP on trade: The application of the WITS-SMART tool with the focus on China [PDF]

open access: yesEconomic Horizons
This paper investigates the effects of RCEP trade creation and trade diversion on China and its sectors, as well as the impact of imports and exports on provinces.
Wenjie Zhang   +2 more
doaj   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

A new approach to modelling the input–output structure of regional economies using non-survey methods

open access: yesJournal of Economic Structures, 2021
This paper proposes a new approach to the regionalization of national input–output tables where suitable regional data are scarce and analysts are considering using location quotients (LQs).
Anthony T. Flegg   +4 more
doaj   +1 more source

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