Results 111 to 120 of about 15,991,872 (294)

The Future of Regional Australia: Change on Our Terms

open access: yes, 2017
Government has diminishing control over the factors that shape Australia's regions. Such factors include the global economy, technological change, the environment and population.
Sorensen, Tony
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Regional Studies

open access: yes, 2012
\ua0La idea central de este eBook es ofrecer un verdadero panorama de las diferentes zonas geográficas en las que se divide el mundo tradicionalmente ya que, hasta la fecha, los libros que existen se concentran en los acontecimientos europeos.
González Mendívil, Georgina
core  

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Panorama y desarrollo de las ciencias sociales en el estado de Tabasco Outlook for and Development of Social Sciences in the State of Tabasco

open access: yesSecuencia, 2011
El presente trabajo presenta el panorama y describe el desarrollo de las reflexiones y diagnósticos del pensamiento social y las ciencias sociales sobre y desde el estado de Tabasco; y las condiciones del entorno social local en el que se practican.
Rodolfo Uribe Iniesta
doaj  

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Distinctive and Innovative Regions: Urban Resilient Communities and Regional Policies. The Sardinia Case Study

open access: yes, 2014
The contemporary research for alternative and sustainable models of development is based on collaborating networks of urban polarities aiming to create an added value for the global territorial system.
USAI, ALESSIA   +2 more
core  

Emerging communities in multilayers networks: analysis of a regional policy programme [PDF]

open access: yes, 2015
With the growing importance of policies sponsoring innovation intermediaries (Howells, 2006; Lazaric et al, 2008; Kauffeld-Monz and Fritsch, 2013; Russo and Rossi, 2009; Caloffi et al, 2015), a need has emerged for appropriate instruments to analyze ...
Annalisa, Caloffi   +5 more
core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

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