Results 91 to 100 of about 15,991,872 (294)

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Scientific findings of Alexander von Humboldt's expedition into the Spanish-American Tropics (1799-1804) from a geographical point of view

open access: yesAnais da Academia Brasileira de Ciências, 2005
Alexander von Humboldt's expedition from 1799 till 1804 to the "equinoctial regions of the new world" led through Venezuela, Cuba, Colombia, Ecuador, Peru, and Mexico.
Gerd Kohlhepp
doaj   +1 more source

The role of regional entrepreneurship ecosystem in the presence of productive firms in the CEE regions [PDF]

open access: yes, 2018
szabadon elérhető / Free accessA World of Flows: Labour Mobility, Capital and Knowledge in an Age of Global Reversal and Regional Revival: 2018.
Páger, Balázs
core  

Towards an Evolutionary Perspective on Regional Resilience

open access: yes, 2015
Boschma R. Towards an evolutionary perspective on regional resilience, Regional Studies. This paper proposes an evolutionary perspective on regional resilience.
Boschma, Ron,, Lund University.
core   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Effective methods of teaching regional studies

open access: yesРазвитие образования
This article provides a detailed analysis of the methods of project and problem-oriented learning. The methods presented by the authors of the article are considered to be the most effective in the process of training students of regional studies in ...
Victoria R. Sagitova   +2 more
doaj   +1 more source

Demographic change and regional competitiveness: The effects of immigration and ageing [PDF]

open access: yes, 2007
The demographic profile of a region is usually seen as a slowly changing background phenomenon in the analysis of regional competitiveness and regional growth. However, regional demographic change can have a significant impact on regional competitiveness
Poot, Jacques
core  

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

The relevance of quantity and quality entrepreneurship for regional performance: the moderating role of the entrepreneurial ecosystem [PDF]

open access: yes, 2018
szabadon elérhető / Free accessA World of Flows: Labour Mobility, Capital and Knowledge in an Age of Global Reversal and Regional Revival: 2018.
Horváth, Krisztina   +3 more
core  

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