Results 71 to 80 of about 15,991,872 (294)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Industrial restructuring FDI and regional development
, 1996 Proceedings of session 3.5, Regional Studies Conference, May 1995, Gothenburg (SE)Available from British Library Document Supply Centre-DSC:98/18067 / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Regional Studies Association, London (United Kingdom) +1 more
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
4th meeting of the Arctic Expert Club of NArFU named after M.V. Lomonosov [PDF]
Арктика и Север, 2016 Editorial Board of the journal +2 more
doaj +1 more source
Regional socio-economic factors influencing diabetes incidence: the case of Romania [PDF]
Eastern Journal of European Studies, 2018 We examine the relation between average net wage, urbanization rate, women density, life expectancy, medical infrastructure and medical human resources, and the incidence of total, insulin, and non – insulin diabetes among Romanians.
Elena DRUICĂ +2 more
doaj
Regional development processes and policies
, 1989 Technologic change, increased international economic competition, and associated reorganization of goods and service producing entities are resulting in a restructuring of economies in the developed world.
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