Results 61 to 70 of about 4,539,160 (346)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Анализ документально-информационного потока по проблемам сибирского краеведения

open access: yesБиблиосфера, 2010
The characteristic of document and information flow on the problems of Siberian regional studies during 1991-2005 is given. The author makes bibliometrical analysis of quantitative changes in document and information flow, its type and aspect and ...

doaj  

Delimitation and Classification of Rural Areas in Hungary [PDF]

open access: yesRomanian Review of Regional Studies, 2016
The present study relies on the outcomes of a complex rural research programme based on the cooperation between the Hungarian Academy of Sciences and the Hungarian National Rural Network.
ÉVA PERGER   +2 more
doaj  

GROWTH OF REGIONAL COMPETITIVENESS ON THE INNOVATION BASIS (in Terms of Prydniprovya Region) [PDF]

open access: yes, 2013
The article demonstrates results of studies concerning solving strategic problem of innovative reformation of economy both at national level and at regional one based upon intensive search of theoretical evidence and their implementation on the basis of ...
Соляник
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Case-srufy: East Asia in World Political and Economic Processes

open access: yesСравнительная политика, 2015
The purpose of the section is to analyze the latest developments in the military and political sphere in East Asia, taking into account a wide range of challenges.
Kseniia Aleksandrovna Efremova   +1 more
doaj   +1 more source

Eurasian Regionalism as a Research Agenda. Interview with Dr. Mikhail A. Molchanov, University of Salamanca, Spain

open access: yesVestnik RUDN. International Relations, 2020
Mikhail Aleksandrovich Molchanov is a prominent Canadian political scholar, professor and publicist. He has worked as a senior policy analyst for the Government of Canada and a professor of political science at several Canadian universities.
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doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

REGIONAL STUDIES AS A COMPLEX OF RESEARCH AND EDUCATIONAL DISCIPLINES IN THE LIGHT OF INTERDISCIPLINARITY

open access: yesСравнительная политика, 2015
The paper is intended to answer the question about the necessity to distinguish between various approaches to reconstruction of interdisciplinarity of regional studies within the scientific and educational fields.
Olga Zinevich
doaj   +1 more source

Labour market performance of immigrants in smaller regions of western countries: some evidence from Atlantic Canada [PDF]

open access: yes, 2010
Despite recent interest in regionalization of immigration in host nations, most studies have analyzed immigrants’ economic performance by largely focusing on their overall national performance. A regional analysis is necessary because changing geographic
Akbari, Ather H.
core  

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