Results 31 to 40 of about 1,232,652 (250)
Oak Ridgidness: Lindsey Freeman’s Longing for the Bomb
Southern Spaces, 2016 Patrick Vitale reviews Lindsey A. Freeman's Longing for the Bomb (Chapel Hill: University of North Carolina Press, 2015).
Patrick Vitale
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Regional Studies, Regional Science, 2020 There is increasing pressure on academics to show the impact of their research. At the same time, policy-makers are expected to draw upon a wide base of evidence, including academic research, to develop innovative solutions to often intractable societal ...
Fiona McKenzie +4 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Anti-Cosmopolitan Campaign in the USSR: Russian Historiography in 2010s – Early 2020s
СибСкриптThe article describes the recent Russian historiography (2010s – early 2020s) on the anti-cosmopolitan campaign launched by the Soviet authorities in 1949–1953. The research relied on the principles of historicism and objectivity.
Elena S. Genina +1 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Online Communication of Local Governments During COVID-19 Pandemic in Hungary
Frontiers in Political Science, 2021 Local governments had key and prominent roles in tackling the COVID-19 pandemic. Their task was to take short-term measures quickly and to organize protection and care for those in need. The main objective of our paper is to present how local governments
Nóra Baranyai +3 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Baltic Region, 2020 Given the unique diversity of Russian regions, regional studies are becoming particularly important for ensuring the stability and development of Russia.
Simonyan R. H., Slutskin L. N.
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