Results 51 to 60 of about 483,079 (267)
Time trend by region of suicides and suicidal thoughts among Greenland Inuit [PDF]
International Journal of Circumpolar Health, 2015 Background: Suicides remain a major public health problem in Greenland. Their increase coincides with the modernization since 1950. Serious suicidal thoughts are reported by a significant proportion of participants in countrywide surveys.
Peter Bjerregaard +1 more
doaj +1 more source
Antimicrobial Resistance – A Silent Pandemic
National Journal of Community Medicine, 2023 Antimicrobial resistance is posing a great threat in many low and middle income countries as a result of groundless and unseemly use of antimicrobial agents in the community.
Sneka P, Sangamithrav, Mahalakshmi K
doaj +1 more source
The regional variation of new technology based firms in Austria [PDF]
, 1998 During the last two decades the role of new business start-ups has gained a growing interest both from regional economics as well as from (regional) economic policy.
Gassler, Helmut, Frohlich, Josef
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients
Frontiers in GeneticsBackgroundMitochondrial acetaldehyde dehydrogenase 2 (ALDH2) plays a critical role in the metabolism of ethanol and nitroglycerin. Mutations in ALDH2 reduce enzymatic activity, impairing nitroglycerin metabolism.
Wenjia Dong +3 more
doaj +1 more source
Regional variation in the use of catheter ablation for patients with arrhythmia in Japan
Journal of Arrhythmia, 2021 Background Regional variation in the use of percutaneous coronary intervention (PCI), especially when performed as an elective procedure, was observed in a previous study.
Takahiro Inoue, Hiroyo Kuwabara
doaj +1 more source
Regional variation in firm formation: Panel and cross-sectional data evidence from Finland [PDF]
, 1998 This paper investigates regional variation in firm formation in Finland between 1989 and 1993. Firstly, the paper describes the firm formation process in 19 regions and 88 subregions, and finds that there has been a clear variation in firm formation ...
Kangasharju, Aki
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Further evidence for regional variation in women's masculinity preferences [PDF]
, 2010 We previously demonstrated that women in countries with poorer health statistics showed stronger attraction to masculine men. Others recently suggested that male-male violence, measured by homicide rates, may be more important than health for regional ...
Jones, Benedict C +14 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source