Results 61 to 70 of about 5,047,269 (302)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
LanguagesIn today’s globalized world, foreign language (FL) communication is characterized by the presence of regional variations that can impact L2 learners’ speech perception in their target language.
Katherine Yaw, Tania Ferronato
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
The regional variation of new technology based firms in Austria [PDF]
, 1998 During the last two decades the role of new business start-ups has gained a growing interest both from regional economics as well as from (regional) economic policy.
Gassler, Helmut, Frohlich, Josef
core
MoleculesBerberis darwinii, known for its bioactive alkaloids like berberine and palmatine, has gained attention for its medicinal properties. However, comprehensive studies on the specific bioactive molecules of Michay are lacking, as previous research has ...
Manuel Chacón-Fuentes +4 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Regional Variations in Cyclical Employment [PDF]
Environment and Planning A: Economy and Space, 1981 In this paper the author develops and tests a model of regional responses to national business-cycles. The model divides cyclical decline in each state into two sectors: a basic sector and a nonbasic sector. The industrial mix, capital—labor ratio, age of capital stock, level of unemployment insurance benefits, labor shortage, and extent of labor-force
openaire +2 more sources
Regional Variation in New Firm Formation in Turkey: Cross-Section and Panel Data Evidence [PDF]
Since the 1980s the promotion of the formation of new firms has been considered as the main policy in dealing with the problem of uneven regional economic development in many countries.
Miyase Yesim Köksal
core +2 more sources
LanguagesIn this article, we analyse durational variation for inherently long consonants in Italian. Productions by 40 speakers of four regional varieties were elicited via a read-aloud task containing target words with inherently long consonants in the post ...
Paolo Mairano +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source