Results 61 to 70 of about 26,753 (310)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Inland Mesolithic settlement in Central Jutland

open access: yesDanish Journal of Archaeology
In Central Jutland there are many traces of settlement throughout the Mesolithic, mostly represented by flint scatters. Yet we do not have a good understanding of the inland Mesolithic, since many sites are palimpsests with mixed flint assemblages from ...
Lone Andersen
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Assessment of population ageing using the statistical method of spatial autocorrelation: a case study of Nitra Region (Slovakia)

open access: yesBulletin of Geography. Socio-Economic Series
This case study presents a comprehensive analysis of the issue of population ageing in the municipalities of the Nitra Region, which in 2022 had the second highest proportion of people of post-productive age (19.5%) among regions in Slovakia and has ...
Gabriela Repaská, Jana Némethová
doaj   +1 more source

SOCIAL ORDERS AND POLITICAL ANALYSIS OF REGIONAL PROCESSES

open access: yesСравнительная политика, 2015
: Contemporary Political Science deals mainly with three major research fields (typology of social order within countries, existing and emerging regional identity and world order in international system), which are studied separately.
A. D. Voskressenski
doaj   +1 more source

Introduction: regionalising the Common Fisheries Policy [PDF]

open access: yes, 2012
The idea of putting together a special issue of MAST on the issue of regionalisation of the Common Fisheries Policy (CFP), was born in late 2010. Having participated in an EU funded research project looking into how an eco-system based approach to ...
Jesper Raakjær, Troels Hegland
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

CONCEPTUAL AND METHODOLOGICAL ANALISYS IN THE STUDY OF REGIONAL DEVELOMPENT IN EU AND, IN PARTICULAR, IN ROMANIA [PDF]

open access: yesCES Working Papers, 2015
Considering that political regionalisation should be more than the division of a territory into regions, its main aim being the regional development of a political entity, this paper seeks to provide answers to the following question: what is the most ...
Raluca Irina CLIPA
doaj  

Design of Homogeneous Territorial Units: A Methodological Proposal [PDF]

open access: yes
One of the main questions to solve when analysing geographically added information consists of the design of territorial units adjusted to the objectives of the study. This is related with the reduction of the effects of the Modifiable Areal Unit Problem
Jordi Surinach Caralt   +2 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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