Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Reducing uncertainty in the american community survey through data-driven regionalization.
PLoS ONE, 2015 The American Community Survey (ACS) is the largest survey of US households and is the principal source for neighborhood scale information about the US population and economy.
Seth E Spielman, David C Folch
doaj +1 more source
Activation of Ras-ERK pathway by Fgf8 and its downregulation by Sprouty2 for the isthmus organizing activity [PDF]
, 2008 In the previous studies, we showed that strong Fgf8 signaling activates the Ras-ERK pathway to induce cerebellum. Here, we show importance of negative regulation of this pathway.
Asuka Suzuki-Hirano +2 more
core +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
A Trade Regime for Sub-National Exports Under the Agreement on the Application of Sanitary and Phytosanitary Measures [PDF]
Regulations relating to disease management have traditionally been an important component of the overall environment in which international trade in agriculture products occurs.
Barichello, Richard R. +2 more
core +1 more source
Reorganizing Corrections: Revisiting the Recommendations of the National Advisory Commission [PDF]
, 1993 In 1973 the National Advisory Commission on Standards and Goals recommended that correctional services be consolidated under a single state agency, arguing that cost efficiencies, improved communication, and greater employee professionalism would result.
Schafer, N. E.
core
Regional brain blood flow in man during acute changes in arterial blood gases [PDF]
, 2012 Chris K. Willie +10 more
openalex +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Malignant Melanoma in the Elderly: Different Regional Disease and Poorer Prognosis [PDF]
, 2011 James B. Macdonald +6 more
openalex +1 more source
The Experience of Using Video Support in Ambulance Care: An Interview Study with Physicians in the Role of Regional Medical Support [PDF]
, 2020 Veronica Vicente +4 more
openalex +1 more source