Results 91 to 100 of about 123,764 (312)

Gobernanza forestal en el territorio Twi Waupasa, Costa Caribe Norte de Nicaragua

open access: yesCiencia e Interculturalidad, 2017
El estudio se realizó con el n de analizar la gobernanza forestal en el territorio Twi Waupasa, Municipio de Puerto Cabezas, Región Autónoma de la Costa Caribe Norte de Nicaragua.
Carlos Mendoza Blanco   +4 more
doaj   +1 more source

REGIONAL THEORY AND REGIONAL MODELS

open access: yesPapers in Regional Science, 1962
The ideas outlined in this paper are tentative and only partially developed. They have arisen very much as a response to the deficiencies in existing regional models. Whether this particular structure can lead to added order and power in such models remains to be demonstrated.
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Factores pedagógicos y socioeconómicos que inciden en el proceso enseñanza –aprendizaje en la modalidad de multigrado bilingüe: idiomas sumu-mayangna, en la comunidad de “Fruta de Pan”, segundo semestre 2007 y primer semestre del 2008.

open access: yesCiencia e Interculturalidad, 2008
El objetivo de esta investigación es analizar los factores pedagógicos y socioeconómicos que inciden en el proceso de enseñanza – aprendizaje en la modalidad de multigrado bilingüe: idiomas sumu-mayangna, en la comunidad de “Fruta de Pan” y en la escuela
Daysi Lackwood Bustillo   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Obstáculos y estímulos a la integración de las regiones atlánticas regresivas

open access: yes, 2001
This article deals with the situation of an Atlantic region marked by the characteristic features of the peripheral regions, such as Asturias. It also investigates the economic reactivation and territorial dynamism actions planned by the regional ...
Benito del Pozo, Paz
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Public capital effects on spanish regions productivity: a non-parametric approach (1965-1998) [PDF]

open access: yes
This paper contributes to the empirical literature on public capital effects on Spanish regions productivity by applying an alternative approach to examine its influence based on a non-parametric FDH production technology with variable scaling parameters
Ramón Mª-Dolores
core  

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