Results 91 to 100 of about 179,751 (258)
Regiones y desarrollo sostenible [PDF]
Las regiones en Colombia no pueden sustraerse hoy de una nueva realidad socioeconómica y ambiental determinada por una etapa más del desarrollo capitalista.
Velásquez Barrero, Luz Stella
core
REGIONAL THEORY AND REGIONAL MODELS
The ideas outlined in this paper are tentative and only partially developed. They have arisen very much as a response to the deficiencies in existing regional models. Whether this particular structure can lead to added order and power in such models remains to be demonstrated.
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
La Costa Caribe de Nicaragua cuenta con una historia caracterizada por la diversidad cultural de los Pueblos Indígenas, Afrodescendientes y Mestizos costeños, razón que determina a la comunidad educativa de URACCAN, entre docentes, personal ...
Neidy Gutiérrez +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
España, durante la primera mitad del siglo XIX, vive un proceso de modernización caracterizado por la transición hacia un régimen liberal constitucional. La realización del censo era primordial, las guerras civiles e inestabilidades políticas impidieron
Antonia Durán Herrera
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Mexico: formación de regiones económicas [PDF]
El propósito básico de la obra es exponer las ideas que muestran el impacto de las etapas históricas y de los factores actuales -tanto de recursos naturales como de ciudades y vías de comunicación, y política económica- en la formación de regiones ...
Bassols Batalla, Ángel
core +1 more source
La gestión del accountability, el caso de Antioquia
La gestión pública tiene dentro de los retos esenciales para su desarrollo, la construcción de metodologías de identificación y valoración de las relaciones sociales.
Luis Fernando Agudelo Henao
doaj +1 more source
The Pacific Rim: Region or regions?
Given the dynamic nature of the Pacific Rim, the Pacific Regional Science Conference Organization (PRSCO) has a unique opportunity to both grow with the region and contribute solutions to the problems which come with growth. This paper first examines some of the economic attributes of the Pacific Region and then explores some of the challenges and ...
openaire +1 more source

