Results 111 to 120 of about 123,764 (312)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Descentralización y gobernanza territorial en Chile: Estado del arte, balance y perspectivas

Revista Venezolana de Gerencia
Este artículo tiene como objetivo determinar la naturaleza de los estudios sobre descentralización y gobernanza territorial en Chile, estableciendo los principales problemas de interés y, a partir de esto, proyectando una agenda de investigación futura ...
Verónica Fuentes, Egon Montecinos, Guillermo Díaz, Luis Vivero   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Las literaturas amazónicas peruanas en la crítica literaria latinoamericana. El caso de Cornejo Polar y Ángel Rama

Tesis (Lima)
Desde el paradigma decolonial se busca evidenciar cuáles son las herramientas teóricas y discursivas de subalternización frente a cualquier forma de pensamiento, sentimiento u organización que no responda a los parámetros europeos.
Julián Galván
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Índice de igualdad regional en instituciones y empresariado para México

Ensayos Revista de Economía
Objetivo: Este estudio desarrolla un índice integral para medir la igualdad regional en el desempeño institucional y empresarial de México, pilares fundamentales del desarrollo económico.
Jonathan Flores Pérez, Vicente Germán-Soto   +1 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Cuadro físico de las regiones ecuatoriales [PDF]

, 1966
Prólogo y notas de Francisco José de Caldas al extracto traducido por él mismo del 'Cuadro físico de las regiones ecuatoriales' de Alexander von Humboldt, publicado en Londres por Mr ...
Caldas, Francisco José de
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Localización industrial en regiones promocionadas

, 1987
Localización industrial en regiones ...
Dichiara, Raúl Oscar, Raúl Oscar Dichiara, Vigier, Hernán Pedro, Hernán Pedro Vigier   +3 more
core   +2 more sources