Development and evaluation of loop-mediated isothermal amplification (lamp) for rapid detection of campylobacter jejuni. [PDF]
Rev Peru Med Exp Salud PublicaCaro-Castro J +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Temporal behavior of proportional mortality of fetal deaths according to underlying cause, 2011-2020. [PDF]
Rev Esc Enferm USPSoares de Barros JR +5 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Productivity convergence in the European regional agricultures. Determinants of its evolution
The aim of this study is to analyse the evolution of the European regional agricultural productivity in terms of convergence. The initial hypothesis is that, in spite of the integration process, the agricultural productivity does not converge to the same
Cuerva Narro, Maria Carmen
core +1 more source
[Shulman syndrome: An atypical presentation of a rare disease]. [PDF]
Rev Med Inst Mex Seguro SocSánchez-Ruiz ÁA +2 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
[Coffin-Lowry syndrome: Case report in Mexico]. [PDF]
Rev Med Inst Mex Seguro SocPérez-Peña AK +2 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
[Autoimmune Regulatory Gene (AIRE) and Development of Autoimmune Thyroiditis in Down Syndrome]. [PDF]
Rev Med Inst Mex Seguro SocMoran-Espinosa MC +5 more
europepmc +1 more source