Results 161 to 170 of about 123,764 (312)

Estatutos de la Asociación América-Europa de Regiones y Ciudades [2005 text no oficial]

, 2005
Aprovats el 16-03 ...
Asociación América-Europa de Regiones y Ciudades
core  

Integrated serosurveillance of multiple communicable diseases in the hinterland of Guyana. [PDF]

Rev Panam Salud Publica
Niles-Robin RA, Sampson A, Valz O, Scott O, Dickson KE, Escalada R, Nicholson D, Woolford J, Paz Ade M, Scholte RC, Luciañez A, Bravo P, Rey-Benito G, Ibarra-Ozcariz S, Morice A, Saboyá-Díaz MI.   +15 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Trends and spatial distribution of precarious work conditions for nurses in Brazil based on the type of employment bond. [PDF]

Rev Lat Am Enfermagem
Aquino ÉC, Guimarães RA, Pagotto DDP, Duarte JA, Silva Filho AID, Borges Júnior CV.   +5 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Estudios socioeconómicos de regiones

, 2011
Tal y como recientemente lo señalaran los informes del Banco Mundial, los proce­sos de aglomeración de las actividades económicas, la urbanización creciente, la eleva­da diversidad socio-demográfica de las ciudades y regiones contemporáneas, así ...
Vivas Pacheco, Harvy
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Update of the spatiotemporal distribution of Aedes albopictus in Ecuador [PDF]

Biomedica
Mora P, Quinatoa P, Morales D.
europepmc   +1 more source

Regions and Regionalism

, 2017
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source