Results 71 to 80 of about 9,964,850 (300)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
New Zealand regions, 1986-2001: Incomes [PDF]
, 2005 This paper investigates income trends in the Regions of New Zealand between 1986 and 2001. It also looks at additional factors of age and ethnicity which have a bearing on the results.
Baxendine, Sandra +3 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
ERS recently constructed a new set of regions depicting geographic specialization in production of U.S. farm commodities. ERS will use the new regions to display results of its analyses in a broad array of venues from briefings to publications, our web ...
Heimlich, Ralph E.
core +1 more source
Star-Forming Regions near GRB 990123 [PDF]
, 1999 We reduced the Hubble Space Telescope Space Telescope Imaging Spectrograph images of the gamma-ray burst GRB 990123 that were obtained on 8-9 February 1999 and find V_0 = 25.36 +/- 0.10, which corresponds to a flux of 0.258 +/- 0.023 micro-Jy for the ...
Hjorth, Jens, Holland, Stephen
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Statistical study of the Russian population’s income and expenditure [PDF]
Известия Саратовского университета. Новая серия: Серия «Экономика. Управление. Право»Introduction. The paper proposes an original author’s approach to the statistical study of income and expenses of Russian residents, based on the presentation of the balance of income and expenses per capita in constant prices of 2023.
Gavel, Olga Yurievna
doaj +1 more source
Economic and competence regions: a descriptive analysis of Danish regions [PDF]
The prosperity of the capital city and surrounding area has been used as one fundamental argument for localisation of large foreign companies. But recent research on regional systems of innovation has emphasised, not just the structure of the system ...
Knudsen, Mette Praest
core
Inner disk regions revealed by infrared interferometry
, 2007 I review the results obtained by long-baseline interferometry at infrared wavelengths on the innermost regions around young stars. These observations directly probe the location of the dust and gas in the disks.
Casse +16 more
core +2 more sources