Results 111 to 120 of about 1,340,538 (293)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Springfield College New Student Register, 1981

open access: yes, 1981
This is the Springfield College New Student Register for 1981. Called by various titles over the years, including Freshman Register, New Student Register, New Student Record, these documents contain portrait photographs of new entering undergraduate ...
Springfield College. Office of Student Affairs;
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Swedish Inflammatory Bowel Disease Register (SWIBREG) – a nationwide quality register

open access: yesScandinavian Journal of Gastroenterology, 2019
Background: Inflammatory bowel disease (IBD) is a chronic, inflammatory relapsing disease with increasing incidence. IBD research and long-term follow-up of patients have, however, been hampered by lack of detailed data on disease phenotype, patient ...
J. Ludvigsson   +15 more
semanticscholar   +1 more source

[Federal Register: Pesticides; Certification of Pesticide Applicators]

open access: yes, 2017
Section of the Federal Register related to rules and regulations established by the U.S. Environmental Protection Agency (EPA) as of January 2017.
United States. Office of the Federal Register.
core  

Springfield College New Student Register, 1982

open access: yes, 1982
This is the Springfield College New Student Register for 1982. Called by various titles over the years, including Freshman Register, New Student Register, New Student Record, these documents contain portrait photographs of new entering undergraduate ...
Springfield College. Office of Student Affairs;
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The completeness of the Swedish Cancer Register – a sample survey for year 1998

open access: yesActa oncologica, 2009
Introduction. The Swedish Cancer Register (SCR) is used extensively for monitoring cancer incidence and survival and for research purposes. Completeness and reliability of cancer registration are thus of great importance for all types of use of the ...
L. Barlow   +3 more
semanticscholar   +1 more source

Analysis of Battery/Generator Hybrid Container Ship for CO2 Reduction

open access: yesIEEE Access, 2018
Ships entering designated emission control areas are required to reduce emission gases drastically, in accordance with international maritime organization regulations or local policies.
Kyunghwa Kim   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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