Results 51 to 60 of about 7,151,646 (328)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Prediction of the COVID-19 Vaccination Target Achievement with Exponential Regression

open access: yesJISA (Jurnal Informatika dan Sains), 2021
The achievement of the national COVID-19 vaccination target in Indonesia is often reported to be uncertain with various existing obstacles. Prediction with exponential regression modeling is done by adopting part of the SKKNI Data Science with the stages
Teja Endra Eng Tju   +3 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Ensemble of Regression-Type and Interpolation-Type Metamodels

open access: yesEnergies, 2020
Metamodels have become increasingly popular in the field of energy sources because of their significant advantages in reducing the computational cost of time-consuming tasks.
Cheng Yan   +5 more
doaj   +1 more source

EXTRA TREES METHOD FOR STOCK PRICE FORECASTING WITH ROLLING ORIGIN ACCURACY EVALUATION

open access: yesMedia Statistika, 2022
Stock is an investment instrument that has risk in its management. One effort to minimize this risk is to model and make further forecasts of stock price movements.
Dani Al Mahkya   +2 more
doaj   +1 more source

Structured count data regression [PDF]

open access: yes, 2003
Overdispersion in count data regression is often caused by neglection or inappropriate modelling of individual heterogeneity, temporal or spatial correlation, and nonlinear covariate effects.
Fahrmeir, Ludwig, Osuna, L.
core   +2 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Drafting Multiannual Local Budgets by Economic-Mathematical Modelling of the Evolution of Revenues [PDF]

open access: yesTheoretical and Applied Economics, 2009
Although seen as a sector with a high degree of inertia and conservatism the public administration system determines the public institutions to record a set of influences both from the internal and external environment.
Ioan Radu   +4 more
doaj  

An Intelligent Event-Sentiment-Based Daily Foreign Exchange Rate Forecasting System

open access: yesApplied Sciences, 2019
Financial time series analysis is an important research area that can predict various economic indicators such as the foreign currency exchange rate. In this paper, a deep-learning-based model is proposed to forecast the foreign exchange rate.
Muhammad Yasir   +6 more
doaj   +1 more source

High Efficiency Intra CU Partition and Mode Decision Method for VVC

open access: yesIEEE Access, 2022
Versatile video coding (VVC/H.266) is the newest video compression standard, which is developed by the Joint Video Experts Team. Compared with previous encoding schemes, VVC achieves higher compression efficiency by introducing a new partition structure ...
Chi-Ting Ni   +3 more
doaj   +1 more source

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