Results 81 to 90 of about 2,943,479 (296)

Lifetime Occupational History, Respiratory Symptoms and Chronic Obstructive Pulmonary Disease: Results from a Population-Based Study

open access: yesInternational Journal of COPD, 2019
Denis Vinnikov,1–3 Aizhan Raushanova,1 Aizhan Kyzayeva,4 Zhanna Romanova,1 Zhangir Tulekov,1 Dinara Kenessary,5 Ardak Auyezova6 1Department of Epidemiology, Biostatistics and Evidence-Based Medicine, al-Farabi Kazakh National University, Almaty ...
Vinnikov D   +6 more
doaj  

Application of an Artificial Neural Network for Efficient Computation of Chemical Activities within an EAF Process Model

open access: yesMetals
The electric arc furnace (EAF) is considered the second most important process for the production of crude steel and is usually used for the melting of scrap.
Alexander Reinicke   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Fisher and Regression

open access: yesStatistical Science, 2005
In 1922 R. A. Fisher introduced the modern regression model, synthesizing the regression theory of Pearson and Yule and the least squares theory of Gauss. The innovation was based on Fisher’s realization that the distribution associated with the regression coefficient was unaffected by the distribution of X.
openaire   +5 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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