Results 181 to 190 of about 3,554,144 (293)

Survival Outcomes in EGFR-Mutant Non-Small Cell Lung Cancer With Brain Metastases: Kaplan-Meier and Cox Regression Analyses Across Treatment Stages. [PDF]

Clin Respir J
Qi H, Qiao Q, Sun X, Xing L.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Sliding down the socioeconomic health gradient of COVID-19 in New York City: multinomial regression analyses of disproportionate financial hardship for Black, Latino, and Asian residents and households with children. [PDF]

Front Public Health
Jimenez R, Dorvil S, Pierre J, Nieves C, Shiman LJ, Shaheen T, Dannefer R, Maulana S, Norvila N.   +8 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Trends in national and ethnic burden of ovarian cancer mortality in South Africa (1999-2018): a population based, age-period-cohort and join point regression analyses. [PDF]

BMC Cancer
Olorunfemi G, Libhaber E, Ezechi OC, Musenge E.   +3 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Regression Analyses and Their Particularities in Observational Studies—Part 32 of a Series on Evaluation of Scientific Publications. [PDF]

Dtsch Arztebl Int
Zapf A, Wiessner C, König IR.
europepmc   +1 more source

Multinomial and ordinal Logistic regression analyses with multi-categorical variables using R. [PDF]

Ann Transl Med, 2020
Liang J, Bi G, Zhan C.
europepmc   +1 more source

Psychological Distress and Its Correlates among Newly Diagnosed People Living with HIV in Northwest Ethiopia: Ordinal Logistic Regression Analyses. [PDF]

Infect Dis (Auckl), 2021
Moges NA, Adesina OA, Okunlola MA, Berhane Y, Akinyemi JO.   +4 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source