Results 91 to 100 of about 4,999,056 (283)
Remote Sensing, 2019 To reduce the impacts of drought, developing an integrated drought monitoring tool and early warning system is crucial and more effective than the crisis management approach that is commonly used in developing countries like Ethiopia.
Yared Bayissa +2 more
doaj +1 more source
Connecting model-based and model-free approaches to linear least squares regression
, 2020 In a regression setting with response vector $\mathbf{y} \in \mathbb{R}^n$ and given regressor vectors $\mathbf{x}_1,\ldots,\mathbf{x}_p \in \mathbb{R}^n$, a typical question is to what extent $\mathbf{y}$ is related to these regressor vectors ...
Davies, Laurie, Duembgen, Lutz
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Model Space Priors for Objective Sparse Bayesian Regression
, 2015 This paper investigates the construction of model space priors from an alternative point of view to the usual indicators for inclusion of covariates in a given model.
Fuentes, Claudio +2 more
core
The Infinite Hierarchical Factor Regression Model [PDF]
, 2008 We propose a nonparametric Bayesian factor regression model that accounts for uncertainty in the number of factors, and the relationship between factors.
Daumé III, Hal, Rai, Piyush
core +6 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Linearization of randomly weighted empiricals under long range dependence with application to nonlinear regression quantiles [PDF]
, 2000 This paper discusses some asymptotic uniform linearity results of randomly weighted empirical processes based on long range dependent random variables+ These results are subsequently used to linearize nonlinear regression quantiles in a nonlinear ...
Mukherjee, Kanchan
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Multimodality in the GARCH Regression Model [PDF]
Several aspects of GARCH(p,q) models that are relevant for empirical applications are investigated. In particular, it is noted that the inclusion of dummy variables as regressors can lead to multimodality in the GARCH likelihood.
Jurgen A. Doornik, Marius Ooms
core