Results 51 to 60 of about 2,018,776 (304)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Evaluation of the Effects of Air Pollution on Hospitalization and Death Due to Corona Crisis in Tehran [PDF]

دانش پیشگیری و مدیریت بحران
Background and objective The COVID-19 pandemic is one of the most important global crises in recent decades. The present study aims to investigate the effect of air pollution on the hospitalization and death rates due to COVID-19 in Tehran, Iran.  Method
Alireza Nazarian, Zahra Abedi, Amir Ashkan Nasiri Pour, Alireza Haji Seyed Mirza Hoseini   +3 more
doaj  

THE DETERMINATS OF THE UNEMPLOYMENT RATE EMPIRICAL EVIDENCE FROM ROMANIA [PDF]

Annals of the University of Oradea: Economic Science, 2010
Among other aspects, the 2007-2009 financial and economic crisis had an impact on the Romanian labor force, too. The aim of this article is to analyze the macroeconomic determinants of the unemployment rate in Romania, using an econometric model.
Pall Katalin, Patka Kinga, Marton Noemi, Kovacs Ildiko   +3 more
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Prediction of low birth weight (LBW) among smokeless tobacco-using pregnant mothers by using stepwise logistic regression model

Indian Journal of Health Sciences and Biomedical Research KLEU
INTRODUCTION: Children's health is tomorrow's wealth is one of the WHO's slogans of the recent years. However, children's health is to a great extent determined by factors that operate in utero, well before they are born. Newborns falling in the category
Praveen Ganganahalli, Satish V Kakade, Jyotsna A Patil, Asha Pratinidhi   +3 more
doaj   +1 more source

Using the classical linear regression model in analysis of the dependences of conveyor belt life [PDF]

Acta Montanistica Slovaca, 2013
The paper deals with the classical linear regression model of the dependence of conveyor belt life on some selected parameters: thickness of paint layer, width and length of the belt, conveyor speed and quantity of transported material. The first part of
Miriam Andrejiová, Daniela Marasová
doaj  

Time Series Forecasting Using a Two-Level Multi-Objective Genetic Algorithm: A Case Study of Maintenance Cost Data for Tunnel Fans

Algorithms, 2018
The aim of this study has been to develop a novel two-level multi-objective genetic algorithm (GA) to optimize time series forecasting data for fans used in road tunnels by the Swedish Transport Administration (Trafikverket).
Yamur K. Al-Douri, Hussan Hamodi, Jan Lundberg   +2 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Graph Huber: a robust regression model for graph data

Xibei Gongye Daxue Xuebao
As it is increasingly prevalent that data contains noise or obeys heavy-tailed distribution, a robust regression model becomes one of focal and hot topics in many study fields.
SU Meihong, WANG Jiaxing, LI Yan, ZHANG Hai   +3 more
doaj   +1 more source

Mapping Maize Water Stress Based on UAV Multispectral Remote Sensing

Remote Sensing, 2019
Mapping maize water stress status and monitoring its spatial variability at a farm scale are a prerequisite for precision irrigation. High-resolution multispectral images acquired from an unmanned aerial vehicle (UAV) were used to evaluate the ...
Liyuan Zhang, Huihui Zhang, Yaxiao Niu, Wenting Han   +3 more
doaj   +1 more source